CORE--BIOSTATISTICS/INFORMATICS

生物统计学/信息学核心将为拟议的口腔癌中心提供实验设计，数据收集和分析以及统计方面的支持。所有项目和核心都将使用这些服务。核心的目标是：a）管理数据收集和数据库整合与链接; B）提供质量控制问题的咨询; c）进行数据统计分析; d）准备数据摘要并帮助研究者准备手稿; 3）支持新的实验和临床设计的统计方面。将通过与匹兹堡大学癌症研究所生物统计设施和数据中心有关的人员的努力提供支持。在十多年的时间里，本中心的生物统计学家与本中心申请的研究人员合作，支持了许多口腔癌临床和基础研究项目。生物统计支持将由Roger Day，Sc.D.指导，数据资源的提供将由UPCI信息学主任亨利洛（医学博士）指导。将这两个数据相关的组成部分统一为一个单一的核心，由Daly和Lowe博士共同领导，将促进口腔癌中心数据处理、处理和分析的各个方面的密切协调。

The Biostatistics/Informatics Core will provide support in experimental design, data collection and analysis and statistics to the proposed Oral Cancer Center. ll programs and cores will use these services The aims of the Core will be: a) to manage data collection and databases integration and linking; b) to provide consultations on issues of quality control; c) to perform statistical analyses of data; d) to prepare data summaries and aid investigators in manuscript preparation; 3) to support the statistical aspects of new experimental and clinical design. Support will be provided through the efforts of personnel associated with the Biostatistics Facility and Data Center of the University of Pittsburgh Cancer Institute. Over a period of more than a decade, biostatisticians in this Core have supported many projects of clinical and basic research in oral cancer, in collaboration with investigators of this Center application. Biostatistical support will be directed by Roger Day, Sc.D., and the provision of data resources will be guided by Henry Lowe, MD, Director of Informatics for the UPCI. The unification of these two data-related components of supported into a single Core with Drs. Daly and Lowe as co-leaders will foster close coordination of all aspects of data handling, processing, and analysis at the Oral Cancer Center.