CORE--PATIENT ACCESS, DATA MANAGEMENT AND TISSUE CULTURE
核心——患者访问、数据管理和组织培养
基本信息
- 批准号:6269197
- 负责人:
- 金额:$ 25.5万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1998
- 资助国家:美国
- 起止时间:1998-03-05 至 1999-02-28
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Therapy-related leukemia is a late complication of treatment with
cytotoxic drugs and/or irradiation. It is a distinctive clinicopathological
and cytogenetic syndrome that is usually fatal. One of the special
features of this program is that the four individual projects are
absolutely dependent upon patient material, since most of the questions
to be addressed arise from the nature of individual patient responses.
That is, why do some patients develop secondary leukemia and others
not? In addition to patient enrollment, chart review, specimen collection
and data acquisition, we propose again to incorporate within the original
Core formal support for database coordination, statistical analysis, and
computation. In addition, we propose to expand our studies on genetic
susceptibility for the development of leukemia by establishing a registry
of primary and secondary leukemia families in order to ascertain familial
aggregations.
The Patient Access core has the dual missions of specimen acquisition
and data management and analysis. These functions are critical to the
successful completion of the proposed investigations and necessary to
support and link together the results that will come from the various
laboratories. In this way, interim analyses of data may be disseminated
promptly among the project investigators, and unique patient resources
may be shared in the most productive manner.
In order to provide an orderly access to patient material and to maintain
records, we propose to continue our Core component to manage these
functions as it has for the past 10 years. Requests for specific clinical
materials (blood or marrow cells, tumor tissues, DNA from buccal swabs,
or cell lines from specific patients or family members) will be directed
by each project PI to the Core. After collection, the clinical specimens
will be logged in and transported for processing and delivery to the
individual projects. Data forms will be kept in secure file cabinets, and
research data will be maintained in electronic files under password
security.
治疗相关性白血病是治疗的晚期并发症
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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RICHARD A LARSON其他文献
RICHARD A LARSON的其他文献
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{{ truncateString('RICHARD A LARSON', 18)}}的其他基金
Patient Access, Data Management, Statistical Analysis, and Tissue Culture
患者访问、数据管理、统计分析和组织培养
- 批准号:
8319538 - 财政年份:2011
- 资助金额:
$ 25.5万 - 项目类别:
Patient Access, Data Management, Statistical Analysis, and Tissue Culture
患者访问、数据管理、统计分析和组织培养
- 批准号:
7512220 - 财政年份:2008
- 资助金额:
$ 25.5万 - 项目类别:
CORE--PATIENT ACCESS, DATA MANAGEMENT AND TISSUE CULTURE
核心——患者访问、数据管理和组织培养
- 批准号:
6325769 - 财政年份:2000
- 资助金额:
$ 25.5万 - 项目类别:
CORE--PATIENT ACCESS, DATA MANAGEMENT AND TISSUE CULTURE
核心——患者访问、数据管理和组织培养
- 批准号:
6102240 - 财政年份:1999
- 资助金额:
$ 25.5万 - 项目类别:
CORE--PATIENT ACCESS, DATA MANAGEMENT AND TISSUE CULTURE
核心——患者访问、数据管理和组织培养
- 批准号:
6236762 - 财政年份:1997
- 资助金额:
$ 25.5万 - 项目类别: