PSYCHOLOGICAL MODEL AND INTERVENTION FOR PEDIATRIC SICKLE CELL DISEASE

小儿镰状细胞病的心理模型和干预措施

• 批准号: 6110144
• 负责人: NADINE Joy KASLOW
• 金额: --
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 1999-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6110144
• 关键词: African American; adolescence (12-20); behavioral /social science research tag; clinical trials; cognitive behavior therapy; disease /disorder proneness /risk; emotional adjustment; family therapy; human subject; human therapy evaluation; mental disorder prevention; method development; middle childhood (6-11); psychological adaptation; psychological models; psychological tests; questionnaires; sickle cell anemia; social adjustment; videotape /videodisc

This research proposes to develop a methodology for assessing and treating youth in whom sickle cell disease (SCD) has been diagnosed. The first aim is to investigate risk and resistance factors associated with children and adolescents' adaptation to SCD. The risk factors to be studied include disease/disability parameters, functional independence, and psychosocial stressors. Intrapersonal and social- ecological variables and stress processing are the resistance factors which will be examined. It is hypothesized that youth high on risk factors and/or low on resistance factors will evidence the most impairment in adaptation, as measured by their mental health, social functioning, and physical well-being. the sample will include 200 female and male children, ranging in age from 8-18, from the Georgia Sickle Cell Center based at Grady Memorial Hospital and from the Egleston Children's Hospital of Emory University. The effects of age, gender, and socio-economic status on functioning across domains will be examined. It is hypothesized that older youth, particularly males from lower class backgrounds, will evidence the greatest impairments in functioning and will report significant risk factors and possess few resistance factors associated with adaptive coping. To examine the relationship between risk and resistance factors and adaptation in children with SCD based upon a risk resistance-adaptation model (1), structural equation modeling will be utilized. The project's second aim is to conduct an initial intervention outcome study comparing a cognitive-behavioral family intervention with a treatment as usual (TAU) control group. Those youth whose initial assessment data reveal them to be high risk, low resistance, and/or poor in psychosocial and psychiatric adaptation will be assigned randomly to either an experimental or control intervention condition. The eight session cognitive-behavioral family intervention focuses on psychoeducation, addressing and managing controllable risk factors, enhancing resistance capacities, and improving adaptive functioning across domains. The two conditions will be compared at a post-treatment assessment and a three month follow-up. It is predicted that youth and families who participate in the experimental condition will evidence enhanced resistance skills and improved psychiatric and psychosocial adaptation.

这项研究建议开发一种评估和 治疗被诊断为镰状细胞病(SCD)的青年。 第一个目标是调查相关的风险和耐药性因素。 儿童和青少年对SCD的适应。的风险因素 需要研究的包括疾病/残疾参数、功能 独立性和心理社会压力。个人内部和社会- 生态变量和胁迫处理是抗性因素。 我们将对其进行审查。据推测，年轻人的风险很高 阻力因素和/或低阻力因素将是最明显的 适应方面的损害，以他们的心理健康、社交能力 身体机能和身体健康。样本将包括200个 来自佐治亚州的男女儿童，年龄从8岁到18岁不等 位于格雷迪纪念医院的镰刀细胞中心 埃默里大学埃格尔斯顿儿童医院。年龄的影响， 关于跨领域运作的性别和社会经济地位将是 检查过了。据推测，年长的年轻人，特别是来自 下层阶级背景，将证明在 功能正常，并将报告重大风险因素，且几乎没有 与适应性应对相关的阻力因素。要检查 高危人群与耐药因素及适应的关系 基于风险抵抗-适应模型的SCD儿童(1)， 将使用结构方程模型。 该项目的第二个目标是进行初步干预结果 认知行为家庭干预与家庭干预的比较研究 常规治疗(TAU)对照组。那些年轻人，他们最初 评估数据显示，它们是高风险、低抵抗力和/或较差的 在心理社会和精神适应方面将被随机分配到 无论是实验干预条件还是对照干预条件。八人组 会话认知-行为家庭干预侧重于 心理教育，应对和管理可控的风险因素， 增强抵抗能力，改善适应功能 跨域。这两种情况将在治疗后进行比较 评估和三个月的随访。据预测，年轻人和 参与实验条件的家庭将提供证据 增强抵抗技能，改善精神和社会心理 适应。