CORE--BIOSTATISTICS

该计划项目的生物统计学核心设施对此是新的 修改后的申请。生物统计核心将提供服务和 向所有调查人员致敬。这将增强每个项目，更好地 确保最有效的设计、计算机数据库的管理和使用 数据整合和分析的统计方法。核心将： 1)提供所有项目的统计设计，2)提供质量 确保数据收集和数据录入，3)制定协调一致的 一种计算机数据库管理系统，用于从所有数据库中获取和集成数据 项目和核心，4)提供假设的生物统计分析，5) 与调查人员协作制定并确定优先顺序 跨项目假设的多变量，以及6)开发和适应 攻击性疾病多个生物标志物分析的统计方法 对比非侵袭性皮肤癌研究。

The Biostatistics Core Facility for the Program Project is new to this revised application. The Biostatistics Core will provide services and collaboration to all investigators. This will enhance each project, better ensure the most effective design, computer data base management and use of statistical methods for integration and analyses of data. The Core will: 1) provide the statistical design of all projects, 2) provide quality assurance of data collection and data entry, 3) develop a coordinated computer data base management system to obtain and integrate data from all projects and cores, 4) provide biostatistical analyses of hypotheses, 5) work collaboratively with investigators to develop and prioritize multivariate, across project hypotheses, and 6) to develop and adapt statistical methods for analyses of multiple biologic markers in aggressive vs. non-aggressive skin cancer research.