CORE--SCIENTIFIC CORE

核心--科学核心

• 批准号: 6204235
• 负责人: EDMOND I EGER
• 金额: $ 13.17万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6204235
• 关键词: analytical chemistry; biomedical facility; fluorohydrocarbon; inhalation anesthesia

The Scientific Core portion of the Program Project provides investigative and administrative support to all investigators. This Core will serve as a resource for Harris, Kendig, and Overduin, who will make use of the expertise in Eger's Laboratory for analysis of anesthetic and non- immobilizer gases/vapors. These analyses will include measurements of these compounds in both liquid and gas phases, and determination of compound solubilities in various solvent phases. Solubilities will be determined at various temperatures to permit interpolation of values for specific experiments. Finally, this Core support will permit the more economical purchase of commercially available fluoroalkanes. The Scientific Core also will enable Eger to make the administrative arrangements needed for the formal biannual meeting of all investigations and will support the travel of investigators at UCSF and consultants to the program to those meetings. (Separate support for travel is requested by subcontracting institutions.) Administrative overview of budgetary matters also will be supported in this Core. Core funding also will support Eger's efforts to ensure the quality of the work that will result from the program (quality control).

该计划项目的科学核心部分为所有调查人员提供调查和行政支持。这个核心将作为哈里斯、肯迪格和奥弗杜因的资源，他们将利用埃格尔实验室的专业知识来分析麻醉和非固定化气体/蒸气。这些分析将包括这些化合物在液相和气相中的测量，以及化合物在不同溶剂相中的溶解度的测定。溶解度将在不同温度下测定，以便为特定的实验提供插值值。最后，这一核心支持将允许更经济地购买市售氟烷烃。科学核心还将使Eger能够为所有调查的正式两年一次的会议做出必要的行政安排，并将支持加州大学旧金山分校的研究人员和项目顾问参加这些会议的旅行。（分包机构要求单独提供旅费。）本核心也将支助预算事项的行政概览。核心资金也将支持Eger的努力，以确保项目的工作质量（质量控制）。