CORE--DATA MANAGEMENT /BIOSTATISTICS

中心角色-DM/BS核心的总体目标是提供 确保实际研究设计、高质量数据的系统 管理和适当的数据分析。在早期 一个中心项目策划阶段，一位资深核心成员出演 通过提供侧重于以下方面的方法帮助，发挥关键作用 研究设计和统计方法。接下来，核心人员提供 在以下数据收集表单的设计方面提供支持服务 集成到网络支持、菜单驱动的数据管理中 系统。在分析阶段，生物统计人员提供 协助分析研究数据和解释 统计结果。无论是核心人员提供咨询还是 直接协助实施数据管理和/或 统计计划取决于项目的需要。具体目标 其核心内容如下：1.项目策划与研究设计。 协助中心调查人员选择一个重点明确、可行的 在早期概念和规划阶段的研究设计 研究项目。B.协助中心调查人员增加 通过平衡假阳性和假阴性来提高每项研究的效率 错误率。C.协助中心调查人员实施多项- 支持同时探索和研究的学习策略 大多数研究的典型验证性目标。2.数据管理a. 协助中心调查人员设计数据收集表格，以 促进研究数据的收集和转让 将信息输入数据管理系统。B.协助中心 研究人员设计和开发安全和 符合人体工程学设计的计算机化数据管理系统。C.至 协助中心调查人员对计算机化数据进行质量控制 管理系统。D.协助中心调查人员 计算机化数据库和分析的文件编制和存档 程序。3.统计方法和分析--a.协助中心 调查人员在统计计划的选择和实施中的作用。B. 协助中心调查人员对研究进行统计分析 数据。C.协助中心调查人员解释 统计结果和编写研究报告。4.咨询 和教学-a.为初学者和正在进行的 咨询研究设计、数据的一般原则 管理和统计方法。B.到教育中心 调查人员、研究员和研究人员关于重要的 关于研究设计、数据管理和统计的问题 方法：研究方法。

Role in the Center - The overall goal of the DM/BS Core is to provide a system for ensuring practical research design, high quality data management, and appropriate analyses of data. During the early planning stage of a Center project, a senior member of the core plays a critical role by providing methodological assistance focusing on research design and statistical approach. Next, core personnel provide support services in the design of data collection forms that are integrated into network-supported, menu-driven data management systems. During the analysis stage, biostatistical staff provide assistance in analysis of the research data and interpretation of statistical results. Whether core personnel provide consultation or direct assistance in the implementation of the data management and/or statistical plan depends on the needs of the project. The specific aims of the core are as follows: 1. Project Planning and Research Design a. To assist Center investigators in choosing a well focused and feasible research design during the early conceptual and planning stages of the research project. b. To assist Center investigators in increasing the efficiency of each study by balancing false positive and false negative error rates. c. To assist Center investigators in implementing multiple- study strategies that support the simultaneous exploratory and confirmatory goals typical of most research. 2. Data Management a. To assist Center investigators in the design of data collection forms to facilitate the collection of research data and transfer of this information into data management systems. b. To assist Center investigators in the design and development of secure and ergonomically-designed computerized data management systems. c. To assist Center investigators in the quality control of computerized data management systems. d. To assist Center investigators in the documentation and archiving of computerized databases and analysis programs. 3. Statistical Methods and Analysis - a. To assist Center investigators in the choice and implementation of statistical plans. b. To assist Center investigators in the statistical analysis of the research data. c. To assist Center investigators in the interpretation of the statistical results and preparation of research reports. 4. Consultation and Teaching - a. To provide a resource for initial an ongoing consultation on the general principles of research design, data management, and statistical methods. b. To educate Center investigators, research fellows, and research staff about important issues regarding research design, data management, and statistical methods.