MUSCLE FUNCTION DURING TERRESTRIAL LOCOMOTION
陆地运动期间的肌肉功能
基本信息
- 批准号:6271875
- 负责人:
- 金额:$ 17.82万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1998
- 资助国家:美国
- 起止时间:1998-04-01 至 1999-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Our objective is to test the common assumption that the muscles doing most
of the work during terrestrial locomotion function isometrically (at
constant length). We hypothesize that during locomotion, muscles function
isometrically only at preferred speeds, and at other speeds they undergo
larger amplitude changes in length. Additionally, we suggest that
isometric activity at preferred speeds produces a minimum in energetic
expenditure (measured as Cost of Transport - Cr), and, muscle length
changes trigger gait transitions. "Preferred speed' refers to the
behavioral tendency for animals to use only a limited set of speeds near
the middle of the much broader range of speeds they are capable of using in
a particular gait. Preferred speeds have been observed in a variety of
different settings, but they are the least well understood of all
locomotory behaviors. Our Specific Aims are: 1) Confirm that the trot-
gallop transition sped and preferred trotting speed are lower when horses
locomote on an incline or carry a load; 2) Compare muscle function, stride
kinematics, and the cost of transport when trotting and galloping on the
horizontal and on a 10% incline, and 3) Compare the same parameters when
trotting and galloping on the horizontal and when carrying a load equaling
20% of body mass. Horses will be used because they are easily trained,
readily exhibit preferred speeds, and their large size facilitates the
measurement of muscle length. We will measure: changes in muscle fiber
length as a function of speed (sonomicrometry), muscle activity (EMG),
preferred speeds, gait transition speeds, and Ct (respirometry). This
research will contribute to our understanding of the function of muscle
during locomotion and the results should be generally true of all
terrestrial locomotion, bipedal as well as quadrupedal. These experiments
will be ideal for MBRS students because the animals are fascinating, the
questions interesting and understandable, and most of the techniques and
data analysis can be quickly learned. This research does not require an
extensive course background, so students can become involved early in their
academic careers when there is the best chance of interesting them in
careers as biomedical researchers.
我们的目标是测试一种常见的假设,即肌肉发挥最大作用
在地面运动过程中的功的等轴测功能(在
固定长度)。我们假设在运动过程中,肌肉的功能
只有在首选速度下和在其他速度下,它们才会等轴测
幅度越大,长度变化越大。此外,我们建议
在首选速度下的等长运动会产生最低的能量
支出(以运输成本-铬衡量),以及肌肉长度
更改触发步态转换。“首选速度”指的是
动物只使用一组有限的速度的行为倾向
他们能够使用的更广泛的速度范围的中间
一种特殊的步态。在各种情况下都观察到了首选速度
不同的环境,但它们是所有环境中最不被理解的
运动行为。我们的具体目标是:1)确认小跑-
当骑马时,疾驰过渡速度和首选小跑速度较低
在斜坡上移动或负重;2)比较肌肉功能,大步
运动学,以及小跑和奔跑时的交通成本
水平和10%倾斜时,以及3)比较相同的参数时
在水平线上小跑和奔跑,当负重相等时
占身体质量的20%。马匹将被使用,因为它们很容易训练,
容易表现出首选的速度,并且它们的大尺寸便于
肌肉长度的测量。我们将测量:肌肉纤维的变化
长度与速度(声学测量)、肌肉活动(EMG)、
首选速度、步态转换速度和Ct(呼吸测量)。这
研究将有助于我们了解肌肉的功能
在运动过程中,结果应该普遍适用于所有人
陆地运动,两足动物和四足动物。这些实验
将是MBR学生的理想选择,因为动物很吸引人,
有趣且容易理解的问题,以及大多数技术和
数据分析可以很快学会。这项研究不需要
广泛的课程背景,因此学生可以及早参与到他们的
在最有可能引起他们兴趣的时候从事学术事业
作为生物医学研究人员的职业。
项目成果
期刊论文数量(0)
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