CORE--MORPHOLOGY

形态核心的目的将是提供最先进的 原位杂交和免疫组织化学支持的参与者 计划项目拨款。核心实验室将a)切割组织切片；b) 进行原位杂交和/或免疫组织化学；以及c)保持 由临床标本和实验模型组成的组织库 可供PPG参与者使用。常见组织库的维护 将显著加强各个实验室的工作并改进 此PPG应用程序中参与者之间的协作。加法 这一原位杂交设施的使用将显著增强 项目负责人分析实验动物模型和 解释抗氧化剂、高血压和血管的体外数据 改建。

The purpose of the Morphology Core will be to provide state-of-the-art in situ hybridization and immunohistochemistry support to participants of the Program Project Grant. The Core laboratory will a) cut tissue sections; b) perform in situ hybridization and/or immunohistochemistry; and c) maintain a tissue bank consisting of clinical specimens and experimental models available for use by PPG participants. Maintenance of a common tissue bank will significantly enhance work in individual labs and improve collaborations between participants in this PPG application. The addition of this in situ hybridization facility will significantly enhance the ability of project leaders to analyze experimental animals models and interpret the in vitro data on antioxidants, hypertension and vascular remodeling.