Born in Scotland in the 2020s - Pilot study

怀孕提供了一个独特的机会，对母亲和婴儿的短期和长期健康结果产生积极影响，从而影响下一代的健康。在这项研究中，我们的目标是进行一项试点研究，以证明建立一个大规模的人口研究的10万名孕妇和他们的孩子，从整个苏格兰招募的可行性。该试点研究将为一个新的“2020年代出生在苏格兰”队列铺平道路，该队列将收集并安全存储从医院，学校和其他来源定期收集的临床，健康和社会数据。然后，这些机密数据将被匿名化，以便在数据分析之前无法识别单个参与者。我们亦会储存血液及尿液样本，这些样本在用作诊断用途后，通常会被弃置。我们将把这些样本与其他数据联系起来，建立一个独特的生物资源，可用于识别不良妊娠结局的新生物标志物。我们的研究将使我们能够了解早期生活经历与后来的健康状况不佳之间的联系，并确定新的干预目标，以改善孕妇及其子女的结局。收集到的丰富和广泛的数据将成为该领域研究人员的宝贵和可持续的资源。

Pregnancy offers a unique opportunity to positively impact on short- and long-term health outcomes of both the mother and baby and thus to influence the health of the next generation. In this study, we aim to conduct a pilot study to demonstrate the feasibility of establishing a large population study of 100,000 pregnant women and their children, recruited from across the whole of Scotland. The pilot study will pave the way for a new "Born in Scotland in the 2020s" cohort which will gather and safely store routinely collected clinical, health and social data from hospitals, schools and others sources. This confidential data will then be then anonymised so that individual participants cannot be identified before data analysis. We will also store blood and urine samples which are left over and normally thrown away after they have been used for diagnostic purposes. We will link these samples to the other data to establish a unique bioresource which can be used to identify new biomarkers for adverse pregnancy outcomes. Our study will allow us to understand the links between early life experiences and later ill health and to identify novel targets for intervention to improve outcomes for pregnant women and their children. The rich and extensive data collected will be a valuable and sustainable resource for researchers in the field.