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TREATMENT OF WILSONS DISEASE WITH ZINC

TREATMENT OF WILSONS DISEASE WITH ZINC
用锌治疗威尔逊氏病
批准号：
6297073
负责人：
GEORGE J BREWER
金额：
$0.02万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6297073
关键词：
clinical research clinical trials copper drug screening /evaluation female hepatolenticular degeneration human pregnant subject human subject human therapy evaluation liver disorder chemotherapy metabolism disorder chemotherapy zinc

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中文摘要
翻译
我们建议将我们的观察扩展到我们的大队列锌治疗的威尔逊氏病患者。相当多的人接受锌治疗10年或更长时间，甚至更多的人接受8年或更长时间。将继续收集大量铜和临床变量的数据。我们的患者群体包括维持治疗，从开始治疗症状前患者，孕妇患者和儿科患者。
英文摘要
We propose to extend our observations on our large cohort of zinc treated patients with Wilson's Disease. A substantial number have been followed for ten years or longer on zinc therapy, and an even larger number for eight years or longer. Data will continue to be collected on a very large series of copper and clinical variables. Our patient groups include maintenance therapy, treatment of presymptomatic patients from the beginning, pregnant patients, and pediatric patients.
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会议论文
PHASE III TRIAL OF TETRATHIOMOLYBDATE (TM) IN PRIMARY BILIARY CIRRHOSIS
PHASE III TRIAL OF TETRATHIOMOLYBDATE IN INITIAL HEPATIC WILSON'S DISEASE
PHASE III STUDY OF DOSE REGIMEN IN INITIAL NEUROLOGICAL WILSON'S DISEASE
PHASE III STUDY OF DOSE REGIMEN IN INITIAL NEUROLOGICAL WILSON'S DISEASE
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