SEGMENTAL ALLERGEN CHALLENGE IN PATIENTS WITH MILD ASTHMA

轻度哮喘患者的局部过敏原挑战

• 批准号: 6112984
• 负责人: Mario Castro
• 金额: $ 2.44万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6112984
• 关键词: active immunization; airborne allergen; asthma; bronchoscopy; clinical research; human subject; respiratory hypersensitivity

Mild asthmatics who develop a late asthmatic response to an allergen inhalational challenge will be studied. Each subject will undergo two bronchoscopic procedures, one for instillation of allergen and diluent and one for performing the biopsies, brushings, and bronchoalveolar lavage. Equal number of subjects will undergo bronchoscopy at 6 and 24 hours post challenge.

轻度哮喘谁开发一个迟发性哮喘过敏原吸入激发反应将进行研究。 每例受试者将接受两次支气管镜检查，一次用于滴注过敏原和稀释剂，一次用于进行活检、刷检和支气管肺泡灌洗。相同数量的受试者将在攻毒后6小时和24小时接受支气管镜检查。