CLINICAL EXPERIENCE AND USE OF VIGABATRIN IN PATIENTS WITH INFANTILE SPASMS

婴儿痉挛是发生在婴儿中的严重类型的癫痫发作。 患有婴儿痉挛症的儿童的前景很差：大多数是发育障碍，大多数继续患有严重的癫痫。 促肾上腺皮质激素是最常用的治疗婴儿痉挛症，是成功的，至少暂时在约70%，但副作用是显着的。传统的抗惊厥药只是偶尔有效。 氨己烯酸，一种新的抗惊厥药物，正在评估其治疗婴儿痉挛症的安全性和有效性。

Infantile spasms are a severe type of seizures which occur in infants. The outlook for a child with infantile spasms is poor: most are developmentally disabled, and a majority continue to have severe epilepsy. ACTH is the most commonly used treatment for infantile spasms and is successful at least temporarily in about 70% However, adverse effects are significant. Conventional anticonvulsants are only occasionally effective. Vigabatrin, a new anticonvulsant is being evaluated for safety and efficacy in treating infantile spasms.