课题基金 / 基金详情

WHOLE LIVER RADIATION DOSE ESCALATION FOR INTRAHEPATIC CANCERS

WHOLE LIVER RADIATION DOSE ESCALATION FOR INTRAHEPATIC CANCERS
肝内癌的全肝脏辐射剂量递增
批准号：
6263650
负责人：
CORNELIUS J MCGINN
金额：
$0.02万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6263650
关键词：
clinical research clinical trials human subject human therapy evaluation liver neoplasms neoplasm /cancer radiation therapy radiation therapy dosage radiobiology whole body irradiation dosage

项目摘要

项目成果

CORNELIUS J MCGINN的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Although radiation has proven efficacy in the treatment of intrahepatic cancers, its usefulness is limited by the low dose that can be tolerated. The dose limiting toxicity is referred to as Radiation Induced Liver Disease (RILD). The pathology of this lesion is identical to that of hepatic veno-occlusive disease (VOD) produced by other causes. This trial will assess the feasibility of whole liver radiation dose escalation utilizing heparin prophylaxis for RILD and alteplase (recombinant tissue-type plasminogen activator, rt-PA) to actively manage RILD should it occur. This strategy has been used successfully to treat hepatic VOD following bone marrow transplant.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
WHOLE LIVER RADIATION DOSE ESCALATION TRIAL UTILIZING ETHYOL AMIFOSTINE
WHOLE LIVER RADIATION DOSE ESCALATION FOR INTRAHEPATIC CANCERS
LOW DOSE LIVER IRRADIATION WITH HEPATIC ARTERIAL CHEMOTHERAPY FOR CANCER
RADIATION DOSE ESCALATION FOR FOCAL LIVER CANCER
海外基金