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TRAUMA AND ORGAN FAILURE--ROLE OF LOCAL LPS BINDING PROTEIN

TRAUMA AND ORGAN FAILURE--ROLE OF LOCAL LPS BINDING PROTEIN
创伤和器官衰竭——局部 LPS 结合蛋白的作用
批准号：
6113513
负责人：
STEWART C WANG
金额：
$2.14万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/6113513
关键词：
binding proteins computer assisted sequence analysis genetic promoter element immunity injury laboratory rat lipopolysaccharides molecular cloning multiple organ failure nucleic acid sequence trauma

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英文摘要
We have demonstrated that lipopolysaccharide protein (LBP) is produced at extrahepatic sites. We are investigating whether this locally- produced LBP affects local immune responses to trauma and injury. As part of these studies, we will be cloning the promoter for the rat LBP gene and require DNA sequence analysis capabilities.
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