DEVELOPMENTAL DETERMINANTS OF UPPER AIRWAY COLLAPSIBILITY

这项研究建议将有助于阐明糖尿病的病理生理学。 儿童阻塞性睡眠呼吸暂停综合征的解剖学研究 神经肌肉因素。对病理生理学有更深入的了解 这种疾病的发生将带来更好的管理和治疗，并可能 最终使我们能够确定哪些患有阻塞性睡眠呼吸暂停综合征的儿童处于危险之中 对于成年后疾病的复发。早期识别 高危患者的早期识别和治疗，以及 有可能预防OSAS的复发。受试者将接受 基线多导睡眠监测以确认他们是正常的或患有阻塞性睡眠呼吸暂停综合征 (这将作为OSAS临床评估的一部分进行 研究对象。

This research proposal will help elucidate the pathophysiology of childhood OSAS by determining the relative roles of anatomic & neuromuscular factors. A better understanding of the pathophysiology of this disease will lead to better management & treatment, & may ultimately allow us to determine which children with OSAS are at risk for recurrence of the disease during adulthood. Early identification of high risk patients will allow for early recognition & treatment, & possibly prevention, of a recurrence of OSAS. Subjects will undergo baseline polysomnography to confirm that they are normal or have OSAS (this will have been done as part of the clinical evaluation in the OSAS subjects.