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ACTG 285 STEM CELL MOBILIZATION AND HARVESTING WITH FILGRASTIM

ACTG 285 STEM CELL MOBILIZATION AND HARVESTING WITH FILGRASTIM
使用 FILGRASTIM 动员和收获 ACTG 285 干细胞
批准号：
6114147
负责人：
Robert Turner Schooley
金额：
$3.22万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6114147
关键词：
cell motility clinical research colony stimulating factor hematopoietic stem cells human subject recombinant proteins

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中文摘要
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英文摘要
ACTG 285 - A Pilot Study of Stem Cell Mobilization and Harvesting from the Peripheral Blood Using Filgrastim. The study explored whether the ability of Filgrastim to mobilize CD34+ stem cells into the peripheral blood differs markedly among individuals with various stages of HIV-1 infection and HIV-1 seronegative individuals. The study's objectives were to determine the safety of stem cell harvesting and to determine the surface phenotypic and functional characteristics of both freshly harvested and cryopreserved stem cells that have been mobilized into the peripheral blood subsequent to the administration of Filgrastim in subjects at various stages of HIV-1 infection. Results of this trial have not yet been published.
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