WHAT FAMILY PROCESSES AFFECT CHILDHOOD ASTHMA OUTCOME?

哪些家庭过程会影响儿童哮喘的结局？

• 批准号: 6114202
• 负责人: FREDERICK Steven WAMBOLDT
• 金额: $ 3.22万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6114202
• 关键词: asthma; behavioral /social science research tag; clinical research; family structure /dynamics; health behavior; human subject; managed care; middle childhood (6-11); patient care management; psychometrics; social group process; therapy compliance

The central aim of this longitudinal study, funded by the NHLBI (1-R01-HL53391) is to clarify the extent to which and the mechanisms whereby specific family processes may be protective or deleterious to adherence behaviors and treatment outcome in 3 groups of asthmatic children, aged 7-12 years: 80 children participating in the Denver site of the Childhood Asthma Management Program (CAMP), 80 children receiving asthma-related care in a large, state-of-the-art, health maintenance organization, and 60 children recruited by using school records to identify children with asthma receiving their care in a variety of different health care systems. The three primary specific aims are: (1) to examine the extent to which family process variables are cross-sectionally associated with and longitudinally influence adherence to asthma treatment, as well as the consistency of this relationship across the three sites -- a clinical trial sample, a managed care sample, and a community treatment sample; (2) to examine the extent to which family process variables are cross-sectionally associated with and longitudinally influence asthma treatment outcome, as well as the consistency of this relationship across the three sites; (3) to determine whether adherence with treatment mediates the relationship between specific family processes and asthma treatment outcome, as well as the consistency of this relationship across the three sites. To date the sample of over 200 children and their families has been recruited and longitudinal follow-up continues. Behavioral coding of these data is being facilitated by the GCRC Psychosocial Assessment Core Laboratory.

这项由NHLBI(1-R01-HL53391)资助的纵向研究的中心目的是阐明特定家庭程序对3组7-12岁哮喘儿童的坚持行为和治疗结果可能起到的保护或有害作用的程度及其机制：80名儿童参加丹佛儿童哮喘管理计划(CAMP)，80名儿童在一个大型的、最先进的健康维护组织接受哮喘相关护理，60名儿童通过使用学校记录来识别在各种不同医疗系统接受护理的哮喘儿童。三个主要的具体目标是：(1)检查家庭过程变量与哮喘治疗依从性的横向关联和纵向影响的程度，以及这种关系在三个地点--临床试验样本、管理护理样本和社区治疗样本--之间的一致性；(2)检查家庭过程变量在横向上与哮喘治疗结果相关并纵向影响哮喘治疗结果的程度，以及这种关系在三个地点的一致性；(3)确定坚持治疗是否调节了特定的家族过程和哮喘治疗结果之间的关系，以及这种关系在三个地点之间的一致性。到目前为止，已经招募了200多名儿童及其家庭的样本，纵向后续行动仍在继续。GCRC心理社会评估核心实验室正在为这些数据的行为编码提供便利。