CALCIUM KINETICS WITH HISTORIES OF OSTEOPOROSIS

低骨量的家族史是发展的危险因素 但导致这一发现的机制不是 知道 低骨量家族史改变 钙代谢在年轻女孩中可能最明显， 大部分骨量是在16岁之前获得的 女性 这项研究的目的是确定是否年轻女孩从 有骨质疏松症病史的家庭， 吸收钙并将其存款骨中的能力。了三个星期 在每次临床研究之前，每个女孩都吃高钙饮食， 选择提供钙的量， 推荐给青春期少女。 在每次研究的当天， 给每个女孩都注射了钙示踪剂 在接下来的5天内钙进入骨的清除率。 到 迄今为止，我们已经完成了3名来自家庭的女孩的临床研究， 有很强的骨质疏松症病史，另外7名女孩将被招募， 本研究 虽然现在对我们的结果发表评论还为时过早， 信息将提供关于以下建议的有用信息： 骨质疏松症家庭的孩子。

A family history of low bone mass is a risk factor for the development of osteoporosis but the mechanisms responsible for this finding are not know. The potential for a family history of low bone mass to alter calcium metabolism may be most apparent in young girls because the majority of bone mass is obtained prior to the age of 16 years in females. The goals of this study are to determine if young girls from families with histories of osteoporosis have alternations in their ability to absob calcium and deposit it into bone. For three weeks before each clinical study, each girl consumes a high calcium diet chosen to provide the amount of calcium which is currently being recommended for adolescent girls. On the day of each study two special forms of calcium tracers are given to each girl so that we can follow the clearance of calcium into bone over the following 5 days. To date,we have completed the clinical study in 3 girls from families with strong histories of osteoporosis, and 7 more girls will be recruited for this study. Although it is too early to comment on our results, this information will provide useful information on the recommendations for children from osteroporotic families.