EFFECT OF LARGE VOLUME PARACENTESIS ON RENAL RESISTIVE INDEX

大容量腹腔穿刺术对肾电阻指数的影响

• 批准号: 6114181
• 负责人: BAHRI M BILIR
• 金额: $ 3.22万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6114181
• 关键词: ascites; clinical research; hormone regulation /control mechanism; human subject; human therapy evaluation; kidney function; therapy

The goal of this study is to investigate the effects of large volume paracentesis on renal blood flow. It is a clinical impression common among gastorenterologists that relieving the pressure in tense ascites will reduce the binding to renal vessels and may improve kidney perfusion. The data supporting this concept is only from trauma literature and bloody ascites. In liver cirrhosis this concept is worthwhile to investigate by a noninvasive accepted method of Doppler - ultrasound examination of renal vessels and a calculated index called renal resistive index. We will also get hormone parameters in ten patients to correlate these findings.

本研究的目的是探讨大容量肾穿刺术对肾血流量的影响。胃肠道科医生普遍认为，缓解紧张性腹水中的压力将减少与肾血管的结合，并可能改善肾脏灌注。支持这一概念的数据仅来自创伤文献和血性腹水。在肝硬化中，这一概念值得通过无创的公认的肾血管多普勒超声检查方法和称为肾阻力指数的计算指数进行研究。我们还将获得10名患者的激素参数，以将这些发现相关联。