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NANDROLONE IN HIV ASSOCIATED WEIGHT LOSS

NANDROLONE IN HIV ASSOCIATED WEIGHT LOSS
诺龙在艾滋病毒相关减肥中的作用
批准号：
6115455
负责人：
Kathleen Mulligan
金额：
$3.1万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6115455
关键词：
AIDS HIV infections androgen analog body composition body weight cachexia clinical research clinical trials drug screening /evaluation functional ability hormone therapy human subject human therapy evaluation immunity injection /infusion intramuscular injections medical complication nutrient intake activity nutrition related tag outcomes research pathologic process quality of life weight loss

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中文摘要
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英文摘要
This is a randomized, double-blind, placebo-controlled study in patients with HIV-associated weight loss. Eligible individuals will receive nandrolone decanoate or placebo by weekly intramuscular injection for 12 weeks. All patients who successfully complete a 12-week placebo- controlled phase will be eligible to receive open-label nandrolone for an additional 12 weeks. Response to treatment will be evaluated by measuring body weight and composition, functional performance, quality of life, and energy and macronutrient intake. Safety, HIV disease progression, and immunologic status will be closely monitored throughout the study.
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