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CYTOGENETIC AND MOLECULAR STUDIES OF PARENTS OF SPONTANEOUS ABORTIONS

CYTOGENETIC AND MOLECULAR STUDIES OF PARENTS OF SPONTANEOUS ABORTIONS
自然流产父母的细胞遗传学和分子研究
批准号：
6115270
负责人：
TERRY J HASSOLD
金额：
$1.92万
依托单位：
CASE WESTERN RESERVE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6115270
关键词：
blood chemistry chromosome disorders clinical research cytogenetics disease /disorder etiology embryogenesis human fetus tissue human subject molecular genetics parents phenotype placenta spontaneous abortion

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英文摘要
The intent of this research project is to utilize tissue samples from spontaneous abortions and blood samples from their parents to answer four questions: 1) How do chromosome abnormalities arise? 2) Is there a correlation between the stage of origin of a chromosome abnormality and the phenotype of the abnormal conception? 3) What is the importance of chromosome abnormalities that are restricted to certain tissues (e.g. placenta)? 4) What is the incidence of chromosome abnormalities in spontaneous abortions? To date 144 subjects have been enrolled into the study. NCRR Clarification: research is on miscarriage
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