EFFECT OF DIETARY POTASSIUM BICARBONATE--SERUM GROWTH HORMONE CONCENTRATION

膳食碳酸氢钾对血清生长激素浓度的影响

• 批准号: 6115221
• 负责人: LYNDA A FRASSETTO
• 金额: $ 4.29万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6115221
• 关键词: bicarbonates; clinical research; diet therapy; dietary potassium; dietary supplements; drug administration rate /duration; female; hormone regulation /control mechanism; human subject; human therapy evaluation; longitudinal human study; nutrition related tag; postmenopause; sleep; somatotropin

Study done in post-menopausal women to determine whether prolonged dietary KHCO3 supplementation increases serum growth hormone concentrations. Serum GH concentrations will be measured during normal nocturnal sleep, and in response to standard GH secretory stimuli (infusion of growth hormone na darginine), pre- and during KHCO3 supplementation. These assessments will be made on two-day admissions per subject, separated by an interval of 4 weeks, for a total of 15 subjects. The study will utilize the GCRC over a period of 2 years.

在绝经后妇女中进行的一项研究，以确定长期饮食是否