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INTERACTION BETWEEN GENE EXPRESSION & DNA DAMAGE DUE TO IONIZING RADIATION

INTERACTION BETWEEN GENE EXPRESSION & DNA DAMAGE DUE TO IONIZING RADIATION
基因表达之间的相互作用
批准号:
6118590
负责人:
JOSEPH L ROTI ROTI
金额:
$0.04万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-08-01 至 1999-07-31

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中文摘要
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英文摘要
A major goal of this research is to synthesize model systems of ionizing radiation damaged DNA and study the effect on transcription in vitro and in vivo. Our recent work has been specifically focused on the design and synthesis of photocleavable DNA building blocks for the production of "caged" DNA single and double strand breaks. Routine high resolution mass spectrometry is required to characterize intermediates in the synthesis of these building blocks
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Radiosensitization by the Cellular Stress Response
  • 批准号:
    7089933
  • 项目类别:
  • 资助金额:
    $165.06万
  • 财政年份:
    2004
  • 负责人:
    JOSEPH L ROTI ROTI
  • 依托单位:
Radiosensitization by the Cellular Stress Response
  • 批准号:
    7475638
  • 项目类别:
  • 资助金额:
    $170.05万
  • 财政年份:
    2004
  • 负责人:
    JOSEPH L ROTI ROTI
  • 依托单位:
Radiosensitization by the Cellular Stress Response
  • 批准号:
    6815325
  • 项目类别:
  • 资助金额:
    $168.79万
  • 财政年份:
    2004
  • 负责人:
    JOSEPH L ROTI ROTI
  • 依托单位:
Radiosensitization by the Cellular Stress Response
  • 批准号:
    6910695
  • 项目类别:
  • 资助金额:
    $163.89万
  • 财政年份:
    2004
  • 负责人:
    JOSEPH L ROTI ROTI
  • 依托单位:
海外基金