COHERENT SCATTERING METHODS IN SOLID STATE NMR

固态核磁共振中的相干散射方法

• 批准号: 6279735
• 负责人: MARCO PRAVIA
• 金额: $ 0.12万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6279735
• 关键词: bioengineering /biomedical engineering; biological products; biomedical resource; nucleic acids; proteins

A form of coherent scattering can be established in magnetic resonance through the interplay of pulsed magnetic field gradients and coherent averaging methods. Consider a sequence where the gradient is restricted to being between RF pulses, then when the gradient evolution is significant during the evolution time of a solid or magic echo sequence, this phase shift dependence of the effective refocusing permits the symmetry of coherent averaging to be reduced and hence the residual dipolar coupling has an anisotropic dependence on the locations of coupled spins. We are using this phenomena in an attempt to create a coherent NMR scattering measurement that will directly measure internuclear distances along the gradient axis. We are using the methods to map out the 1-bond distance in a dilute 2-spin system via double quantum filtered dipolar coupled exchange.

在磁场中可以建立一种形式的相干散射 通过脉冲磁场梯度和脉冲磁场梯度的相互作用产生的共振 相干平均法。考虑一个序列，其中梯度是 限制为在RF脉冲之间，然后当梯度 在固体或魔法的进化时间内，进化是重要的 回波序列，这种相移依赖于有效的重聚焦 允许降低相干平均的对称性，因此 剩余偶极子耦合具有各向异性依赖 耦合自旋的位置。我们正在利用这种现象来试图 为了创建一个相干的核磁共振散射测量，它将直接 测量沿梯度轴的核间距离。我们正在使用 稀薄2-自旋体系中1-键距的作图方法 通过双量子滤波偶极耦合交换。