课题基金 / 基金详情

PIVOTAL EFFICACY STUDY OF INHIBITION OF GASTRIC ACID SECRETION BY PANTOPRAZOLE

PIVOTAL EFFICACY STUDY OF INHIBITION OF GASTRIC ACID SECRETION BY PANTOPRAZOLE
泮托拉唑抑制胃酸分泌的关键功效研究
批准号：
6118462
负责人：
JOSEPH R PISEGNA
金额：
$0.19万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6118462
关键词：
Zollinger Ellison syndrome antiulcer drug benzimidazoles clinical research clinical trials drug screening /evaluation endocrine neoplasm gastric acid gastric juice inhibitor gastrointestinal disorder chemotherapy human subject human therapy evaluation intravenous administration secretion stomach surgery

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The objective is to identify the regimens of intravenously(IV) administered pantoprazole that would decrease and maintain acid secretion at less than 10mEq/ hr in patients with Zollinger-Ellison syndrome (ZES) with or without multiple endocrine neoplasia-type I (MEN-I) syndrome who have not under- gone partial gastrectomy and at less than 5 mEq/hr in those patients with ZES with or without MEN-I who have undergone parital gastrectomy and to minor safety.
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