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INDWELLING BALLOON CATHETER FOR COMBINED POSTOPERATIVE INTRACAVITY PHOTODYNAMIC

INDWELLING BALLOON CATHETER FOR COMBINED POSTOPERATIVE INTRACAVITY PHOTODYNAMIC
用于联合术后腔内光动力的留置球囊导管
批准号:
6119325
负责人:
HENRY HIRSCHBERG
金额:
$2.46万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-04-01 至 2000-03-31

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中文摘要
翻译
一种留置气囊导尿管敷贴器,可用于 腔内负荷性近距离放射治疗或光动力治疗 (光动力疗法)已经发展了大约一周的时间。这个 切除腔稳定,几何形状简单,以确保 要求照射的均匀性。涂抹器被放置在 肿瘤切除后,在所产生的腔中心和 充气的气球或多或少地填满了空洞。导尿管是 通过皮肤带出,并调整为1-2厘米突出 在头皮表面以上。在加载后,接受了近距离放射治疗 10-12分,最高可达72分。在一系列试验中几乎没有发现副作用。 72例患者中。630 nm激光的光能传递是 发现非常高效和统一,特别是当气球 充满了扩散的液体。一种新的治疗方案 分次腔内近距离放射治疗与PDT的联合应用 现在正在计划中。
英文摘要
An indwelling balloon catheter applicator which can be used for either intracavity after loading brachytherapy or photodynamic therapy (PDT) over a period of approximately one week has been developed. The resection cavity is stabilized, and geometrically simple to insure the uniformity of irradiation required. The applicator was positioned after tumor resection in the center of the resulting cavity and the balloon inflated to more or less fill the cavity. The catheter was brought out through the skin and adjusted so that 1-2 cm projected above the scalp surface. After loading brachytherapy was give in 10-12 fractions up to 72 gy. Few side effects were noted in a series of 72 patients. The transfer of light energy from a 630 nm Laser was found highly efficient and uniform especially if the balloon was filled with a diffusing liquid. A new treatment protocol employing the combination of both frationated intracavity brachytherapy and PDT is now being planned.
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BYPASSING THE BLOOD BRAIN BARRIER: MONOCYTES AND MACROPHAGES
  • 批准号:
    8362707
  • 项目类别:
  • 资助金额:
    $0.16万
  • 财政年份:
    2011
  • 负责人:
    HENRY HIRSCHBERG
  • 依托单位:
MODULATED IMAGING OF RAT GLIOMA
  • 批准号:
    8362678
  • 项目类别:
  • 资助金额:
    $0.51万
  • 财政年份:
    2011
  • 负责人:
    HENRY HIRSCHBERG
  • 依托单位:
INCREASING DRUG DELIVERY INTO TUMORS
  • 批准号:
    8362711
  • 项目类别:
  • 资助金额:
    $0.16万
  • 财政年份:
    2011
  • 负责人:
    HENRY HIRSCHBERG
  • 依托单位:
MODULATED IMAGING OF RAT GLIOMA
  • 批准号:
    8169507
  • 项目类别:
  • 资助金额:
    $0.34万
  • 财政年份:
    2010
  • 负责人:
    HENRY HIRSCHBERG
  • 依托单位:
海外基金