New insights into female reproductive tract formation and tubulogenesis.

目的：本项目旨在通过研究女性生殖道的发育起源，提高我们对其形成的认识。大多数女性生殖道来自一对被称为<s:1>勒氏管的胚胎管，其形成尚不完全清楚。意义：利用鸡和小鼠模型和创新的遗传方法，该项目将揭示<s:1>勒氏管形成的新基因和细胞途径。预期结果：这项工作将提高在生物科学领域的知识，在女性生殖和生物系统中如何形成管。好处：它将培养研究科学家，发展合作，并提高澳大利亚在生殖领域的崇高地位。

Aims: This project aims to improve our understanding of female reproductive tract formation by studying its developmental origins. Most of the female reproductive tract derives from a pair of embryonic tubes called Müllerian ducts, the formation of which is incompletely understood. Significance: Using chicken and mouse models and innovative genetic approaches, the project will undercover novel genes and cellular pathways in Müllerian duct formation. Expected outcomes: This work will enhance knowledge in the biological sciences, in the area of female reproduction and how tubes form in biological systems. Benefits: It will train research scientists, develop collaborations and enhance Australia’s high standing in the field of reproduction.