SPIN LABELING STUDIES OF NORMAL RECOMBINANT & MUTANT HUMAN SERUM ALBUMINS

正常重组的旋转标记研究

• 批准号: 6118869
• 负责人: CHARLES PETERSON
• 金额: $ 0.49万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-03-01 至 2000-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6118869
• 关键词: bacteria; bioengineering /biomedical engineering; biological products; biomaterials; biomedical resource; enzymes; hormones; proteins

A recombinant human serum albumin (HSA) expressed in yeast and several HSA mutants were studied by circular dichroism and spin label ESR methods to establish their structural integrity and characterize drug-protein interactions.

一种在酵母中表达的重组人血清白蛋白（HSA）， 用圆二色性和自旋标记法研究了几种HSA突变体 ESR方法，以确定其结构完整性并表征 药物-蛋白质相互作用