ICF: Unmanned aerial vehicles ('drones') for sustainable vaccine research and improving equity in vaccine delivery: a feasibility study in The Gambia
ICF:用于可持续疫苗研究和提高疫苗交付公平性的无人机(“无人机”):冈比亚的可行性研究
基本信息
- 批准号:MR/X011771/1
- 负责人:
- 金额:$ 12.84万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Research Grant
- 财政年份:2022
- 资助国家:英国
- 起止时间:2022 至 无数据
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
In low-income countries in sub-Saharan Africa, conducting internationally competitive health research, and providing high quality healthcare to all, requires numerous motor vehicle journeys. Many of these journeys are of short distance (<30 km) and are undertaken to transport small, light-weight payloads including vaccines, medicines, blood transfusions and research samples (e.g., blood samples from adults and children in clinical trials). However, due to poor road conditions and the need for flexible, robust, long-lived vehicles, most journeys are currently undertaken in diesel- or petrol-powered four-wheel-drives. Vehicles like this are some of the least efficient and most environmentally- and health-damaging modes of transport operating.Emissions of greenhouse gases from vehicles in Africa are increasing by 7% each year. Climate change is already impacting on food security in Africa as well as changing the spread of diseases like malaria and yellow fever that result from mosquito bites. Leadership to reduce these emissions is therefore important. Vehicles, particularly older vehicles, also produce air pollutants which increase the risk of heart and lung disease, diabetes, and strokes. These are diseases that are already increasing rapidly in Africa so new ways to reverse this trend are needed. Environmental noise (or noise pollution) comes mainly from traffic in urban settings in sub-Saharan Africa and can cause sleep and mood disturbances, difficulties concentrating and heart disease. Slowing down increases in these diseases is important too. Finally, road traffic deaths are going down across much of the world, but are increasing in many parts of Africa. They are currently the most common cause of death in 15 to 29-year-olds in West Africa, with nearly half of these deaths being pedestrians. Reducing vehicle numbers through looking at other modes of transport is also one way which may address this important burden.This study will establish the feasibility, costs, and environmental impacts of using unmanned aerial vehicles (or 'drones') to replace road vehicles for the transport of research samples and healthcare supplies in The Gambia, West Africa. The drones will be solar changed and thus carbon neutral with respect to power.We will specifically test drones first, to transport blood samples from participants in vaccine studies to a central laboratory for processing, and second, to transport hepatitis B vaccines to rural health posts allowing newborn babies to receive the vaccines on the first day of life as recommended.Factors including the length of flights (time and distance), the ability to maintain blood samples and vaccines at stable temperatures, power consumption, costs, and safety as well as the impacts of seasonal factors, such as storms and the harmattan winds from the Saharan, on flights will all be explored. This technical data will be complemented by interviews and group discussions aiming to gain a broader understanding of how drone flights are likely to be perceived in The Gambia and other comparable settings. The study will be conducted in partnership with the Gambian Ministry of Health and Arda, a company aiming to develop drone technology for the purposes described in Africa. Through these partnerships the future impact of the study on environmentally sustainable research and healthcare are expected to be maximized.
在撒哈拉以南非洲的低收入国家,开展具有国际竞争力的卫生研究并向所有人提供高质量的卫生保健,需要进行多次机动车辆旅行。其中许多行程距离较短(<30公里),用于运输小型、轻型有效载荷,包括疫苗、药品、输血和研究样本(例如临床试验中成人和儿童的血液样本)。然而,由于恶劣的道路条件和对灵活、坚固、寿命长的车辆的需求,目前大多数旅行都是在柴油或汽油驱动的四轮驱动中进行的。像这样的交通工具是效率最低、对环境和健康危害最大的交通工具之一。非洲汽车排放的温室气体以每年7%的速度增长。气候变化已经影响到非洲的粮食安全,并改变了疟疾和黄热病等由蚊子叮咬引起的疾病的传播。因此,减少这些排放的领导作用非常重要。车辆,尤其是老旧车辆,也会产生空气污染物,增加患心脏病、肺病、糖尿病和中风的风险。这些疾病已经在非洲迅速增加,因此需要新的方法来扭转这一趋势。环境噪音(或噪音污染)主要来自撒哈拉以南非洲城市环境中的交通,可导致睡眠和情绪障碍、注意力难以集中和心脏病。减缓这些疾病的增长也很重要。最后,道路交通死亡人数在世界大部分地区都在下降,但在非洲许多地区却在增加。它们目前是西非15至29岁人群中最常见的死亡原因,其中近一半的死亡是行人。通过寻找其他交通方式来减少车辆数量也是解决这一重要负担的一种方法。本研究将确定在西非冈比亚使用无人驾驶飞行器(或“无人机”)取代公路车辆运输研究样本和医疗保健用品的可行性、成本和环境影响。这些无人机将采用太阳能发电,因此在电力方面是碳中和的。我们将专门测试无人机,首先将疫苗研究参与者的血液样本运送到中心实验室进行处理,其次,将乙肝疫苗运送到农村卫生站,让新生儿在出生的第一天就按照建议接种疫苗。包括飞行时间(时间和距离)、在稳定温度下保存血液样本和疫苗的能力、电力消耗、成本和安全以及季节性因素(如风暴和来自撒哈拉的哈马丹风)对飞行的影响在内的因素都将得到探讨。这些技术数据将通过访谈和小组讨论加以补充,旨在更广泛地了解无人机飞行在冈比亚和其他类似环境中可能被如何感知。这项研究将与冈比亚卫生部和Arda公司合作进行,Arda公司旨在为非洲描述的目的开发无人机技术。通过这些伙伴关系,预计这项研究对环境可持续研究和保健的未来影响将得到最大限度的发挥。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Ed Clarke其他文献
The waning of maternal measles antibodies: A multi-country maternal-infant seroprevalence study
母体麻疹抗体的减弱:一项多国母婴血清流行率研究
- DOI:
10.1016/j.jinf.2025.106531 - 发表时间:
2025-08-01 - 期刊:
- 影响因子:11.900
- 作者:
Karen S. Tiley;Hinke ten Hulscher-van Overbeek;Sudha Basnet;Rob van Binnendijk;Ed Clarke;Stephen Cose;Duc Anh Dang;Ha Thi Thu Hoang;Beth Holder;Olubukola T. Idoko;Beate Kampmann;Freddie Kibengo;Fiona van der Klis;Abdul Momin Kazi;Elke Leuridan;Kirsten Maertens;Herberth Maldonado;Mary Nyantaro;Saad Omer;Marcela F. Pasetti;Merryn Voysey - 通讯作者:
Merryn Voysey
The normal function of the immune system in a clinical context
- DOI:
10.1016/j.paed.2012.11.014 - 发表时间:
2013-03-01 - 期刊:
- 影响因子:
- 作者:
Ed Clarke - 通讯作者:
Ed Clarke
Circulation of respiratory viruses during the COVID-19 pandemic in The Gambia [version 2; peer review: 2 approved]
冈比亚 COVID-19 大流行期间呼吸道病毒的传播[第 2 版;
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:0
- 作者:
S. Jarju;Elina Senghore;H. Brotherton;Alasana Saidykhan;Samba Jallow;Ebrima Krubally;Edrisa Sinjanka;Morris Ngor Ndene;Fabakary Bajo;Musa M Sanyang;B. Saidy;Alasana Bah;Nuredin Mohammed;Karen Forrest;Ed Clarke;U. Dalessandro;A. Sesay;Effua Usuf;Carla Cerami;A. Roca;B. Kampmann;T. I. Silva;I. Asante;Antonia Ho - 通讯作者:
Antonia Ho
HPV vaccination acceptance and perceptions related to fertility and population control in the Gambia: An anthropological analysis
- DOI:
10.1016/j.vaccine.2023.04.072 - 发表时间:
2023-06-01 - 期刊:
- 影响因子:
- 作者:
Rose J. Wilson;Lamin Leigh;Haddy Bah;Heidi J. Larson;Ed Clarke - 通讯作者:
Ed Clarke
Safety of the novel oral poliovirus vaccine type 2 (nOPV2) in infants and young children aged 1 to <5 years and lot-to-lot consistency of the immune response to nOPV2 in infants in The Gambia: a phase 3, double-blind, randomised controlled trial
2型新型口服脊髓灰质炎疫苗(nOPV2)在1至<5岁婴幼儿中的安全性以及冈比亚婴幼儿对nOPV2免疫反应的批次间一致性:一项3期双盲随机对照试验
- DOI:
10.1016/s0140-6736(23)02844-1 - 发表时间:
2024-03-23 - 期刊:
- 影响因子:88.500
- 作者:
Magnus Ochoge;Ahmed Cherno Futa;Ama Umesi;Lucy Affleck;Larry Kotei;Baboucarr Daffeh;Ebrima Saidy-Jah;Anna Njie;Oluwafemi Oyadiran;Bassey Edem;Musa Jallow;Edrissa Jallow;Simon A Donkor;Erman Tritama;Talha Abid;Kathryn A V Jones;Bernardo A Mainou;John O Konz;Alan Fix;Chris Gast;Ed Clarke - 通讯作者:
Ed Clarke
Ed Clarke的其他文献
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{{ truncateString('Ed Clarke', 18)}}的其他基金
HPV, STI and AMR in West Africa: estimating population burden and understanding exposures to accelerate vaccine impact and drive new interventions
西非的 HPV、STI 和 AMR:估计人口负担并了解暴露情况,以加速疫苗的影响并推动新的干预措施
- 批准号:
MR/W002116/1 - 财政年份:2022
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
A non-inferiority trial to assess the safety and immunogenicity of yellow fever vaccine dose sparing strategies for campaign and programmatic use
一项非劣效性试验,旨在评估用于运动和规划使用的黄热病疫苗剂量节约策略的安全性和免疫原性
- 批准号:
MC_EX_MR/R006148/1 - 财政年份:2017
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
A randomised, observer-blind, non-inferiority trial to evaluate alternative human papillomavirus vaccination schedules in young females in West Africa
一项随机、观察者盲法、非劣效性试验,旨在评估西非年轻女性的替代人乳头瘤病毒疫苗接种计划
- 批准号:
MC_EX_MR/N006070/1 - 财政年份:2015
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
A randomised controlled trial to evaluate the effect of maternal or neonatal pneumococcal conjugate vaccination on pneumococcal carriage in early life
一项随机对照试验,旨在评估孕产妇或新生儿肺炎球菌结合疫苗接种对生命早期肺炎球菌携带的影响
- 批准号:
MC_EX_MR/M007529/1 - 财政年份:2014
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
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