WEB-BASED METHODS RESOURCE CENTER FOR EYE DISEASE TRIALS

描述：（申请人的摘要）互联网近年来已经发展 从大学和政府实体使用的有限操作到 这是几乎所有组织日常工作的基本结构， 公共和私人，以及数百万的个人用户。使用Web为 研究性学习在节约成本、减少 人员需求和数据质量。在多中心临床试验中，Web 技术拓宽了协调中心之间的通信线路 和偏远地区，以至于许多标准试验的转换 功能的在线处理不仅是可取的和可行的，但总之， 秩序将成为必需品。 根据我们在这一领域已有的丰富经验， 要求资金开发基于网络的例程， 适用于临床试验和流行病学研究， 国家眼科研究所，并建立一个资源中心，以促进他们的 使用.该提案的具体目标是： - 为眼科人员开发基于网络的培训和认证程序 参与多中心临床试验的视力检测。 - 为NEI资助的临床试验建立一个资源中心， Jaeb健康研究中心的培训和认证测试 - 为临床试验开发基于网络的患者视力测试。 我们已经开发了一个基于网络的培训和认证计划， 儿童视力测试。我们现在建议将这项技术扩展到 为标准屈光度和ETDRS视力制定类似的计划 常规用于测量视力的成人临床试验的方案。我们 我相信这个程序将得到广泛的使用，并期望它被用于 所有NEI试验均使用ETDRS字符测量视力。所以我们会 为所有NEI资助的临床试验建立资源中心， 使用儿科和ETDRS的视力测试人员的培训和认证 协议.我们相信，这样一个中心不仅将提高数据质量， NEI试验，但也将减少进行许多试验的成本。发展 基于网络的实际视力测试程序是一个自然的延伸， 我们已经完成的工作。这也是一种资源 用于所有NEI试验测量视力。

DESCRIPTION: (Applicant's Abstract) The internet has evolved in recent years from a limited operation used by university and government entities to a structure fundamental in the daily routine of virtually all organizations, both public and private, and millions of individual users. The use of the web for research studies has a number of advantages in terms of cost savings, reduced personnel needs, and data quality. In multi-center clinical trials, web technology has broadened the communication lines between coordinating centers and remote sites to such an extent that the conversion of many standard trial functions to online processing is not only desirable and feasible but in short order will become a necessity. Building upon our already considerable experience in this area, this proposal requests funding to develop web-based routines that will have broad applicability to the clinical trials and epidemiologic studies supported by the National Eye Institute and to establish a resource center to facilitate their use. The specific objectives of the proposal are to: -Develop web-based training and certification routines for ophthalmic personnel involved in visual acuity testing in multi-center clinical trials. -Establish a resource center for the NEI-funded clinical trials for web-based training and certification testing at Jaeb Center for Health Research -Develop web-based patient visual acuity testing for clinical trials. We have already developed a web-based training and certification program for pediatric visual acuity testing. We now propose to extend t his technology to develop a similar program for the standard refraction and ETDRS visual acuity protocols routinely used in adult clinical trials measuring visual acuity. We believe that this program will gain widespread use and expect it to be used by all NEI trials measuring visual acuity with the ETDRS chars. Therefore, we will establish a resource center for all of the NEI-funded clinical trials for training and certification of vision testers using both the pediatric and ETDRS protocols. We believe that such a center will not only enhance data quality in NEI trials but will also reduce the costs to conduct many trials. Development of a web-based program for actual visual acuity testing is a natural extension of the work we have already done. This, too, can be expected to be a resource for all NEI trials measuring visual acuity.