Web-Based Methods Resource Center for Eye Disease Trials

描述(由申请人提供)：这项建议是为了提供资金，以维持一个资源中心，以开发和维护计算机相关的应用程序和设计，对NEI支持的研究具有广泛的适用性。Jaeb卫生研究中心的Web资源中心成立于2000年，目的是开发对NEI研究有价值的基于Web的例程和其他与因特网有关的过程。到目前为止，该中心已经开发了多种基于互联网的对象，包括学习网站和在线培训和认证应用程序。该中心还进入了有利于NEI研究的其他与计算机相关的领域，包括开发计算机化视力测试仪系统、成人和儿童计算机化视力测试以及无纸化临床研究程序。 申请资助期的具体资源中心目标如下： 1.为电子视力(EVA)测试仪开发其他视力测试应用程序和选项 A.使用触摸屏输入设备和/或语音识别在EVA上开发E-ETDRS测试程序的患者自测版本，并进行研究以评估其可行性和有效性 B.使用LEA符号(或其他图片)为EVA开发视力测试应用程序，以测试两岁儿童的视力，并进行研究以评估其可行性和有效性。 C.开发一种比E-ETDRS更有效的视力测试算法，并进行一项研究以评估其可靠性和效度 D.开发一个交互式网络应用程序，用于培训和认证修改后的ETDRS折射协议 E.开发用于执行修改后的ETDRS验光协议的EVA应用程序。 2.将电子视力测试仪(EVA)系统扩展为可由用户安装在任何通用PC克隆计算机(包括笔记本电脑)上的便携式程序包。 3.为NEI资助的研究目前使用的视力测试系统提供技术支持，并为有兴趣使用该系统的NEI资助的新研究提供系统。 4.维护为NEI资助的研究开发的网站和应用程序，并根据新项目的需要开发新的网站和应用程序。 5.继续就临床研究的网络方法，包括使用触摸屏平板电脑获取数据，与NEI资助的其他研究合作和咨询。 6.开发和推广无纸化临床研究方法和程序。

DESCRIPTION (provided by applicant): This proposal is for funding to maintain a resource center to develop and maintain computer related applications and designs with broad applicability to NEI-supported studies. The Web Resource Center at the Jaeb Center for Health Research was established in 2000 to develop web-based routines and other internet related processes that would be of value to NEI studies. To date the center has developed multiple internet-based objects including study websites and online training and certification applications. The center has also advanced into other computer- related areas of benefit to NEI studies including the development of a computerized visual acuity tester system, adult and child computerized visual acuity tests, and procedures for paperless clinical studies. The specific resource center aims for the requested funding period are as follows: 1. Develop additional vision testing applications and options for the Electronic Visual Acuity (EVA) tester a. Develop a patient self-test version of the E-ETDRS testing procedure on the EVA using a touch screen input device and/or voice recognition and conduct a study to assess its feasibility and validity b. Develop a visual acuity testing application for the EVA using Lea symbols (or other pictures) to test visual acuity in two year olds and conduct a study to assess its feasibility and validity. c. Develop a more efficient visual acuity testing algorithm than E-ETDRS and conduct a study to assess its reliability and validity d. Develop an interactive web application for training and certification in the modified ETDRS refraction protocol e. Develop an EVA application for performing the modified ETDRS refraction protocol. 2. Extend the Electronic Visual Acuity tester (EVA) system as a portable package that can be user-installed on any generic PC clone, including a laptop computer. 3. Provide technical support for vision testing systems in current use by NEI-funded studies and provide systems to new NEI-funded studies interested in using this system. 4. Maintain websites and applications that have been developed for NEI-funded studies and develop new sites and applications as needed for new projects. 5. Continue collaboration and consulting with other NEI-funded studies on web-based methods for clinical studies, including the use of touch screen tablet PCs for data capture. 6. Develop and extend paperless clinical studies methodology and procedures.