课题基金 / 基金详情

ERADIAMR

ERADIAMR
埃拉迪亚
批准号:
MR/Y033892/1
负责人:
Stefano Pagliara
金额:
$38.44万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2024
资助国家:
英国
项目状态:
未结题
起止时间:
2024 至 --
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中文摘要
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英文摘要
Antimicrobial resistant bacteria are one of the major health challenges of the 21st century. In 2019 alone, nearly 5 million deaths were associated with failure to treat infections caused by resistant bacteria. There is a clear and urgent need to find new ways to detect antimicrobial resistant bacteria more rapidly and more effectively. The ERADIAMR project will develop a new way of detecting antimicrobial resistant bacteria by looking at the way live bacteria vibrate. In fact, we have recently discovered that when bacteria are treated with a specific antibiotic drug, they vibrate in a different way depending on whether they are susceptible or resistant to the antibiotic in use. Sensing these vibrations requires only 4 hours and therefore will allow us to understand very quickly which antibiotic needs to be used to cure an infection. In contrast, currently it can take longer than a day for a physician to decide which antibiotic should be used with current standard methods. In this project we will look at the vibrations of bacteria that typically infect humans and against which there is an urgent need to find the best antibiotic treatment. Therefore, the new technology that we will develop will allow in the future to rapidly detect and treat infections due to resistant bacteria and save lives.
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DYNBIOTICS - Understanding the dynamics of antibiotics transport in individual bacteria
  • 批准号:
    EP/Y023528/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $215.83万
  • 财政年份:
    2024
  • 负责人:
    Stefano Pagliara
  • 依托单位:
Understanding molecular accumulation in single cells via microfluidics and omics
  • 批准号:
    BB/V008021/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $65.26万
  • 财政年份:
    2021
  • 负责人:
    Stefano Pagliara
  • 依托单位: