BODY REPRESENTATIONS--NEUROPSYCHOLOGY AND ANATOMIC BASIS

描述：（改编自申请人的摘要） 调查旨在促进目前有限的理解， 大脑表征的本质和解剖学基础 人体这些表征包括身体意象、身体图式和 车身结构描述一组受试者 单侧中风将在一系列任务中进行测试，以确定 身体表征障碍的患病率，并定义解剖学 通过将性能与病变部位相关联， 通过神经影像学研究确定。那些表现出 涉及特定类型的身体表征的损伤将作为 第二系列研究的主题，旨在定义身体 陈述将作为第二系列研究的主题， 来定义这些效应背后的机制。一系列 将进行调查，以评估可能的治疗作用 针对身体图式的干预措施。最后，一系列 将使用功能磁共振成像在正常人中进行研究， 假设的身体表征的解剖学基础。 所提出的研究具有临床和理论意义 意义从理论上讲，这些研究将提供 对身体认知结构的重要见解 表示。这项工作的潜在临床意义也是 清楚如果像假设的那样，身体图式对行动至关重要， 针对这种表现的干预措施可能具有重要的 治疗意义

DESCRIPTION: (Adapted From The Applicant's Abstract) The proposed investigations are intended to advance the currently limited understanding of the nature and anatomic bases of the brain's representations of the human body. These representations include the body image, body schema and body structural description. An unselected group of subjects with unilateral stroke will be tested on a battery of tasks to determine the prevalence of disorders of body representation and to define the anatomic bases of these effects by correlating performances with lesion site as defined by neuro-imaging studies. Those patients who demonstrate impairments involving specific types of body representations will serve as subjects in a second series of studies aimed at defining of body representations will serve as subjects in a second series of studies aimed at defining the mechanisms that underlie these effects. A series of investigations will be performed to assess the possible therapeutic role of interventions targeting the body schema. Finally, a series of investigations in normals using fMRI will be performed to investigate the anatomic underpinnings of the postulated body representations. The proposed investigations have both clinical and theoretical significance. From a theoretical standpoint, these studies would offer important insights into the cognitive architecture of body representations. The potential clinical significance of this work is also clear. If, as hypothesized, the body schema is crucial to action, interventions targeting this representations may have important therapeutic implications.