VALIDATION OF TRANSILLUMINATION AND THE NEVOSCOPE

透射照明和电子显微镜的验证

• 批准号: 2869811
• 负责人: NIZAR A MULLANI
• 金额: $ 10万
• 依托单位: TRANSLITE, LLC
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2869811
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; early diagnosis; imaging /visualization /scanning; melanoma; neoplasm /cancer diagnosis; pigments; skin disorder diagnosis; skin neoplasms

DESCRIPTION: The investigators propose to test the clinical utility of their trans-illumination device for the imaging and diagnostic discrimination of malignant from non-malignant pigmented skin lesions, as further described by their abstract: "Melanoma is a lethal skin cancer that has a very high cure rate if detected early. A prototype device for early detection of melanoma, called the Nevoscope, has been built by Tranlite. It produces transillumination and epiluminescence images of pigmented lesions that are similar to the oil based epiluminescence but without the need for oil or the glass face-plate and could be a major innovation for early detection of melanoma. "In Phase I we will show, by imaging 80 pigmented lesions with the nevoscope, the feasibility of improving the detection accuracy for dysplastic nevi and melanoma compared to visual examination of oil based epiluminescence. We will also test a new prototype of the Nevoscope using white light emitting diodes which will significantly lower the price of the device and make it useful in other areas of medicine. "In Phase II we will develop and test the LED based nevoscope device for early detection of melanoma and other medical applications of skin imaging. The commercial goal of Translite is to significantly lower the price of a hand-held Nevoscope device that can be easily afforded by most physicians." PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述：研究人员建议测试他们的临床效用 用于成像和诊断辨别的透射照明装置 恶性来自非恶性色素性皮肤病变，如进一步描述的 他们的摘要： “黑色素瘤是一种致命的皮肤癌，如果被发现，治愈率非常高 早期的。一种用于早期检测黑色素瘤的原型设备，称为 Nevscope，由 Tranlite 制造。它产生透照和 与油基类似的色素病变的落光图像 落光，但不需要油或玻璃面板，并且可以 成为黑色素瘤早期检测的一项重大创新。 “在第一阶段，我们将通过用血管镜对 80 个色素病变进行成像来展示， 提高发育异常痣检测精度的可行性 黑色素瘤与油基落光目视检查的比较。我们将 还测试了使用白光发光二极管的 Nevscope 的新原型 这将显着降低该设备的价格并使其在 其他医学领域。 “在第二阶段，我们将开发和测试基于 LED 的血管镜设备，以便尽早实现 检测黑色素瘤和皮肤成像的其他医学应用。这 Translite 的商业目标是大幅降低手持设备的价格 大多数医生都可以轻松负担得起 Nevescope 设备。” 拟议的商业应用：不可用