ONCOLOGY QOL CLINICAL SIGNIFICANCE CONSENSUS MEETING

申请人的描述（Applicant's Description） 该提案的目的是举行一次协商一致会议， 肿瘤学生活质量（QOL）测量的临床意义。 的 这次协商一致会议的主要成果将是编写一本专著， 列出了评估临床的主要方法、挑战和解决方案 肿瘤学中QOL测量的意义。 我们将汇集20个 将这一专题的主要专家召集到一个“智囊团”，其目标是 就这一主题做一个科学总结。 我们将找出六个 围绕临床意义评估的主要问题， 由三至五名专家组成的小组， 会议之前。 会议形式将有针对性地促进 20名专家讨论和完善6份文件草案 in QOL生活质量research研究. 这些文件随后将汇集成一个单一的专题论文 将于2001年春季出版。 2001年秋季，我们将举办一个 第二次会议，开放登记，以更充分地讨论和传播 共识会议产生的材料。 因此，最终产品 这次会议的主题是阐述科学的现状， 评估肿瘤学中QOL测量的临床意义。 这将 为所有肿瘤学研究人员提供切实的利益， 挣扎于如何测量生活质量和评估何时 发生了具有临床意义的变化。

DESCRIPTION (Applicant's Description) The purpose of this proposal is to hold a consensus meeting on assessing clinical significance for quality of life (QOL) measurement in oncology. The major outcome of this consensus meeting will be to produce a monograph which sets out the primary methods, challenges, and solutions for assessing clinical significance for QOL measurement in oncology. We will bring together twenty of the leading experts on this topic to a "think tank", with the goal of producing a state-of-the-science summary on this topic. We will identify six primary issues surrounding the assessment of clinical significance and assign teams of three to five of the experts to prepare draft summary documents in advance of the meeting. The meeting format will be targeted to promote the discussion of and refinement of the six draft documents by the twenty experts in QOL research. These documents subsequently will be gathered together into a single monograph to be published in the spring of 2001. In the fall of 2001, we will host a second meeting with open registration to discuss more fully and disseminate the material produced from the consensus meeting. Hence the ultimate product of this meeting will be to set out the state of the science in terms of assessing clinical significance for QOL measurement in oncology. This will provide tangible benefit to all oncology researchers who at present are struggling with the basic problem of how to measure QOL and to assess when a clinically significant change has occurred.