GORDON RESEARCH CONFERENCE ON REPRODUCTIVE TRACT BIOLOGY

本申请要求为将于2000年7月2日至7日举行的生殖道生物学戈登会议提供部分资金。请注意，由于会议的科学内容，我们要求国家儿童健康和人类发展研究所作为会议的主要赞助商。 我们还请求妇女健康办公室、国家癌症研究所、国家糖尿病、消化和肾脏疾病研究所、国家环境健康科学研究所和国家普通医学研究所的联合赞助。 要求赞助的国家数目反映了这次会议的不寻常性质，这次会议的重点是男性和女性生殖道器官和器官系统的生物学和病理学，而不是具体的分子或过程。 因此，本次会议吸引了来自各种领域和背景的参与者，从基础科学到临床实践。 因此，本次会议的主要目标是促进跨学科交流和整合有关生殖道的信息。 三个具体目标将使我们能够实现这一目标：第一，会议的科学内容将达到最高水平。 为了达到这一卓越标准，我们邀请了在各自领域最前沿的国际公认的专家作为演讲者。 有一个有趣的混合已建立的研究人员谁一直在各自领域的领导者多年来和同样著名的研究人员在其他领域的转基因小鼠的表型分析发现了这些分子在生殖道意想不到的和新颖的行动。 第二，非常重视与重要临床问题高度相关的研究，并有可能转化为医疗实践。 例如，一个完整的会议集中在激素信号的机制，在乳腺的背景下，特别强调畸变，导致乳腺癌。第三，非常强调学生和初级同事的参与，因为任何领域的未来都取决于下一代研究人员。 总之，我们计划了一次令人兴奋的会议，这与生殖道生物学戈登会议的丰富传统是雅阁的，该会议已经存在了近30年。 我们设想，新的网站（康涅狄格学院，新伦敦康涅狄格州）和意图，以满足在一个永久的基础上与哺乳动物配子发生和胚胎发生会议将提高这次会议的质量，这一直是由与会者评价极高。

This application requests partial funding for the Reproductive Tract Biology Gordon Conference to be held July 2-7, 2000. Please note that due to the scientific content of the meeting we request the National Institute of Child Health and Human Development as the primary sponsor of the meeting. We also request joint sponsorship by the Office of Women's Health, the National Cancer Institute, National Institute of Diabetes, Digestive and Kidney Diseases, the National Institute for Environmental Health Sciences, and the National Institute of General Medical Sciences. The number of requested sponsors reflects the unusual nature of this conference which focuses on the biology and the pathology of the organs and organ systems of the male and female reproductive tracts, rather than on specific molecules or processes. Therefore, this meeting attracts participants from a wide variety of fields and backgrounds ranging from basic science to clinical practice. Accordingly, the principal goal of this conference is to stimulate cross- disciplinary exchange and integration of information concerning the reproductive tract. Three specific aims will allow us to accomplish this goal: First, the scientific content of the meeting will be at the highest level. To achieve this standard of excellence, we are inviting speakers who are internationally recognized experts at the forefront of their fields. There is an interesting blend of established investigators who have been leaders in their respective areas for many years and equally renowned researchers in other fields whose phenotypic analyses of transgenic mice have uncovered unexpected and novel actions of these molecules in the reproductive tract. Second, there is a strong emphasis on research that is highly relevant to important clinical questions and has potential for translation into medical practice. For example, one entire session focuses on mechanisms of hormonal signaling in the context of the mammary gland with a special emphasis on aberrations that lead to breast cancer. Third, there is a strong emphasis on the inclusion of students and junior colleagues because the future of any field depends on the next generation of investigators. In summary, we have planned an exciting meeting that is in accord with the rich traditions of the Reproductive Tract Biology Gordon Conference, which has been in existence for nearly 30 years. We envision that the new site (Connecticut College, New London Connecticut) and the intent to meet on a permanent basis with the Mammalian Gametogenesis and Embryogenesis Conference will enhance the quality of this meeting, which has consistently been rated extremely high by the attendees.