OBSERVER PERFORMANCE STUDIES-READER SELECTION & TRAINING

观察者表现研究——读者选择

• 批准号: 6192933
• 负责人: DAVID GUR
• 金额: $ 19.74万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-05-01 至 2003-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6192933
• 关键词: behavioral /social science research tag; bioimaging /biomedical imaging; case history; clinical research; diagnosis design /evaluation; diagnosis quality /standard; health care personnel performance; human data; imaging /visualization /scanning; method development; neoplasm /cancer radiodiagnosis; statistics /biometry

DESCRIPTION (Adapted from Applicant's Abstract): Many of the investigations that are now carried out during imaging systems' evaluations and comparisons include interpretation (reading) studies of normal and abnormal cases that are evaluated by receiver operating characteristics (ROC) or derivatives thereof. Unfortunately, if one takes into account case and reader representativeness, most studies would require prohibitively large sample sizes and a large number of readers in order to produce adequate statistical power for a statistically significant discrimination between reading nodes in a manner that is both clinically relevant and generalizable. Approaches to case and observer selection protocols for these studies in this field have been largely arbitrary (and frequently suboptimal). The applicants propose to investigate the possibility that the implementation of specific case and reader selection protocols could allow one to focus on limited clinical questions that can be conclusively answered with an observer performance study while requiring a small effort; hence, making such studies much more feasible and reasonable to perform. During the prior effort, the applicants reported focusing their investigation on case selection issues. While they proposed to continue to investigate several aspects in this regard, the current proposal would focus on the possible effects of observer (reader) selection and training on study design and results.

描述（改编自申请人的摘要）：许多研究 现在在成像系统的评估和比较过程中， 包括正常和异常情况解释（阅读）研究， 通过受试者工作特征（ROC）或其衍生物进行评估。 不幸的是，如果考虑到案例和读者代表性， 大多数研究需要非常大的样本量和大量的 为了产生足够的统计功效， 阅读节点之间的显著区别， 临床相关性和可推广性。对案件和观察员的处理办法 在这一领域，这些研究的选择协议在很大程度上是任意的 (and经常是不理想的）。申请人建议调查 具体实施的可能性和读者选择 协议可以让人们专注于有限的临床问题， 最后回答了观察员的性能研究，同时要求 小的努力;因此，使这些研究更加可行和合理， 表演。在之前的努力中，申请人报告说，他们的工作重点是 调查案件选择问题。虽然他们建议继续 调查这方面的几个方面，目前的建议将侧重于 观察者（阅片者）的选择和培训对研究的可能影响 设计和结果。