Digital Breast Tomosynthesis (DBT) in a Screening Environment: a Prospective Stud
筛查环境中的数字乳腺断层合成 (DBT):一项前瞻性研究
基本信息
- 批准号:7763035
- 负责人:
- 金额:$ 31.44万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-12-01 至 2013-11-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAgreementBenignBreastClinicalClinical ResearchConsentDataDiagnosticDigital MammographyDiseaseEnvironmentImageInformation SystemsLaboratoriesMalignant NeoplasmsParticipantPerformancePlayPositioning AttributeProceduresProspective StudiesQualifyingRadiology SpecialtyReaderReportingResearch DesignRetrospective StudiesRoleSample SizeScreening procedureSiteSpecificitySystemTechnologyTestingTimeWomanWomen&aposs GroupWorkarmbaseclinical practiceclinically relevantdesigndigitaldigital imagingfollow-upimaging modalityimprovedinclusion criteriainterestmeetingsoperationprospectivepublic health relevanceradiologistresearch study
项目摘要
DESCRIPTION (provided by applicant): Recent advances in digital imaging, including but not limited to Full Field Digital Mammography (FFDM), has enabled a relatively easy implementation of Digital Breast Tomosynthesis (DBT) technology into the clinical practice. DBT based imaging alone and /or in combination with FFDM is of great interest in screening as well as in diagnostic breast imaging for several reasons. To date questions remain regarding the role that DBT may ultimately play in breast imaging. It is clear that significant work needs to be done in terms of both the systems themselves and, as important perhaps, how to best manage and display the generated image data. However, at this time it is most important to confirm in a prospective clinical study the demonstrated potential for a significant decrease in recall rates when using DBT, as shown in retrospective studies. The purpose of this project is to address this very point by performing a limited prospective study on women who are most likely to benefit from the inclusion of DBT in the screening environment. We propose to assess and compare the recall rates in younger women (<55YO) participating in their initial breast screening examination. The work proposed here is aimed primarily at the use of DBT imaging in combination with FFDM in the screening environment, but this project has broad and potentially significant implications on diagnostic breast imaging as well.
PUBLIC HEALTH RELEVANCE: This is a prospective study to test the hypothesis that the use of DBT in the screening environment actually reduces recall rates by at least 20%. A unique study design will enable the testing of this primary hypothesis, as well as important clinically relevant secondary hypotheses, on the group of women who are most likely to benefit from this imaging and examination management approach.
描述(由申请人提供):数字成像的最新进展,包括但不限于全场数字乳房x线摄影(FFDM),使得数字乳房断层合成(DBT)技术相对容易地应用于临床实践。基于DBT的单独成像和/或联合FFDM在筛查和诊断乳腺成像中有很大的兴趣,原因有几个。迄今为止,DBT在乳腺成像中最终可能发挥的作用仍然存在疑问。显然,在系统本身以及如何最好地管理和显示生成的图像数据方面都需要做大量的工作,这一点可能同样重要。然而,在这个时候,最重要的是在前瞻性临床研究中确认使用DBT时显着降低召回率的潜力,如回顾性研究所示。该项目的目的是通过对最有可能从DBT筛查中获益的女性进行有限的前瞻性研究来解决这一问题。我们建议评估并比较参加首次乳房筛查检查的年轻女性(<55岁)的召回率。本文提出的工作主要是针对DBT成像与FFDM在筛查环境中的结合使用,但该项目在乳腺成像诊断方面也具有广泛和潜在的重要意义。
项目成果
期刊论文数量(0)
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{{ truncateString('DAVID GUR', 18)}}的其他基金
Reducing false positives during interpretations of ultrasound examinations for breast cancer screening
减少乳腺癌筛查超声检查解读过程中的误报
- 批准号:
9250095 - 财政年份:2016
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$ 31.44万 - 项目类别:
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$ 31.44万 - 项目类别:
Digital Breast Tomosynthesis (DBT) in a Screening Environment: a Prospective Stud
筛查环境中的数字乳腺断层合成 (DBT):一项前瞻性研究
- 批准号:
7995217 - 财政年份:2009
- 资助金额:
$ 31.44万 - 项目类别:
Breast Cancer Risk Stratification with Resonant Electrical Impedance Spectroscopy
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$ 31.44万 - 项目类别:
Breast Cancer Risk Stratification with Resonant Electrical Impedance Spectroscopy
使用共振电阻抗谱进行乳腺癌风险分层
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7804524 - 财政年份:2007
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$ 31.44万 - 项目类别:
Breast Cancer Risk Stratification with Resonant Electrical Impedance Spectroscopy
使用共振电阻抗谱进行乳腺癌风险分层
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$ 31.44万 - 项目类别:
Comparing Performance Under FROC Paradigm - A Non Parametirc Approach
比较 FROC 范式下的性能 - 非参数方法
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$ 31.44万 - 项目类别:
Comparing Performance Under FROC Paradigm - A Non Parametirc Approach
比较 FROC 范式下的性能 - 非参数方法
- 批准号:
7258805 - 财政年份:2006
- 资助金额:
$ 31.44万 - 项目类别:
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