SEX VS GENDER IN PAIN PERCEPTION

疼痛感知中的性别与性别

• 批准号: 6199560
• 负责人: Michael E ROBINSON
• 金额: $ 23.51万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2004-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6199560
• 关键词: behavioral /social science research tag; chronic pain; clinical research; expectancy; gender difference; human subject; pain threshold; sex roles; social perception

Recent reviews of the literature suggest that men and women may differ in their perception of pain. A number of explanations have been proposed for why women report more pain in experimental pain studies, may respond differently to analgesic medication and have a higher incidence of a number of pain conditions. Previous explanations have included possible sex differences in the organization of the central nervous system, differences in peripheral tissue composition and qualities, and the influence of sex hormones. The influence of social learning and social role expectations has been largely ignored in these studies in favor of the investigation of more first-order biological explanations of sex differences in pain responding. This project proposes to investigate the relative contribution of biological sex and psychosocially determined sex-role constructs to differences between men and women in pain responsivity. Directly comparing sex and sex-role (gender role) constructs will allow for the testing of two main hypotheses: 1) The sex differences in laboratory, experimental pain studies are influenced by gender role expectations and social learning to an equal or greater degree than first-order biological influences; 2) The discrepancy between clinical and experimental pain differences between men and women is a function of social learning influences on the willingness to report stimulation as painful which is differentially active in the two settings. This project will employ the measurement of experimental pain, clinical pain (patients with chronic facial pain), and novel pain protocols that combine laboratory psychophysics with clinically relevant stimuli to directly test the previously mentioned hypotheses. In addition, two studies are proposed which directly manipulate a leading social learning construct (gender role) to test their influences on pain responsivity in men and women.

最近对文献的评论表明，男性和女性对疼痛的感知可能不同。对于为什么女性在实验性疼痛研究中报告更多疼痛，对止痛药的反应可能不同，以及多种疼痛状况的发生率更高，已经提出了许多解释。之前的解释包括中枢神经系统组织中可能的性别差异，外周组织成分和质量的差异，以及性激素的影响。在这些研究中，社会学习和社会角色期望的影响在很大程度上被忽略了，而是倾向于调查更多关于疼痛反应中性别差异的一级生物学解释。该项目建议调查生物性别和心理决定的性别角色结构对男性和女性疼痛反应差异的相对贡献。直接比较性别和性别角色(性别角色)结构将允许检验两个主要假设：1)实验室中的性别差异，实验疼痛研究受到性别角色期望和社会学习的影响，程度与一阶生物学影响相同或更大；2)男性和女性临床和实验疼痛差异是社会学习影响将刺激报告为疼痛的意愿的函数，这在两种环境中都不同。这个项目将使用实验疼痛、临床疼痛(慢性面部疼痛患者)的测量，以及将实验室心理物理学与临床相关刺激相结合的新型疼痛方案，以直接测试前面提到的假设。此外，还提出了两项研究，它们直接操纵领先的社会学习结构(性别角色)，以测试它们对男性和女性疼痛反应的影响。