Discovering the cell of origin for rare ovarian cancers

发现罕见卵巢癌的起源细胞

• 批准号: nhmrc : 2002943
• 金额: $ 59.94万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/discovering-cell-origin-ovarian-cancers/1780035
• 关键词: Discovering; cell; origin; rare; ovarian

Ovarian cancer has many different varieties, and even though they all grow at the ovary, for some types we don't know the cell where the cancer starts. Using novel sequencing methods, this study will find the tissue of origin for two rare subtypes. This finding will help us to develop appropriate pre-clinical models that we can use to test emerging cancer therapies. Identifying the cell of origin will provide key insights into early detection or even prevention of these rare but deadly diseases.

卵巢癌有很多不同的类型，尽管它们都生长在卵巢，但对于某些类型，我们不知道癌症是从哪里开始的。利用新的测序方法，本研究将找到两种罕见亚型的起源组织。这一发现将帮助我们开发合适的临床前模型，我们可以用来测试新兴的癌症疗法。确定起源细胞将为早期发现甚至预防这些罕见但致命的疾病提供关键见解。