KNOWLEDGE PROCESSING FOR CLINICAL PRACTICE GUIDELINES

这是香农奖，为这项研究提供部分支持 项目低于指定研究所的资助范围，但 都在最优秀的边缘。香农奖旨在提供 支持测试该方法的可行性；开发进一步的测试 改进研究方法；对可用的数据进行二次分析 数据集；或执行可演示PI的离散项目 研究能力或导致额外的重量已经有价值的 申请。以下应用程序取自原始文档 由首席调查员提交。 本提案描述了旨在支持信息学的研究。 开发、实施和评估的要求 临床实践指南。这项工作预计将导致 制定经改进的指导方针，并随之产生 结构化的、计算机可访问的医学知识存储库， 可用于决策支持。包含以下内容的研究计划 提出了4个具体目标： (L)设计和推广建模和 使用扩充决策表处理指导知识。方法 将被定义为处理指导知识的复杂性和 不确定性。 (2)提炼和传播知识的技术 获取临床指南，并进行验证以确保其一致性 和全面性。与美国儿科学会合作， 新制定的指导方针将事先进行逻辑分析和验证 到出版。 (3)评估以指导方针为基础的决策支持的有效性 改善国家门诊指南依从性的设备 儿童哮喘的管理。一项随机对照试验将是 用来衡量哮喘监测系统对指南的影响 依从性、遭遇记录、患者结果和护理成本。 (4)开发一套支持以下内容的交互式计算机应用程序 用于广泛管理的决策和临床工作流 常见的儿科问题。从临床试验中获得的知识 将与工作流分析、合理的应用程序设计相结合 原则和先进的数字技术，创造有用和可用的 指导方针实施的工具。 个别提供商将从决策的可用性中受益 支持基于指南知识的应用程序。从公共卫生角度来看 从角度看，有效实施循证指导方针 哮喘等儿科常见病的门诊管理 应有助于减少不适当的做法，并 提高了护理质量。

THIS IS A SHANNON AWARD PROVIDING PARTIAL SUPPORT FOR THE RESEARCH PROJECTS THAT FALL SHORT OF THE ASSIGNED INSTITUTE'S FUNDING RANGE BUT ARE IN THE MARGIN OF EXCELLENCE. THE SHANNON AWARD IS INTENDED TO PROVIDE SUPPORT TO TEST THE FEASIBILITY OF THE APPROACH; DEVELOP FURTHER TESTS AND REFINE RESEARCH TECHNIQUES; PERFORM SECONDARY ANALYSIS OF AVAILABLE DATA SETS; OR CONDUCT DISCRETE PROJECTS THAT CAN DEMONSTRATE THE PI'S RESEARCH CAPABILITIES OR LEAD ADDITIONAL WEIGHT TO AN ALREADY MERITORIOUS APPLICATION. THE APPLICATION BELOW IS TAKEN FROM THE ORIGINAL DOCUMENT SUBMITTED BY THE PRINCIPAL INVESTIGATOR. This proposal describes research intended to support informatics requirements for the development, implementation, and evaluation of clinical practice guidelines. The work is expected to result both in the development of improved guidelines and, concomitantly, to produce structured, computer-accessible repositories of medical knowledge that can be used for decision support. A research program with the following 4 specific aims is proposed: (l) To devise and extend fundamental techniques for modeling and processing guideline knowledge using augmented decision tables. Methods will be defined to deal with guideline knowledge complexity and uncertainty. (2) To refine and disseminate techniques by which knowledge can be acquired for clinical guidelines and verified to assure its consistency and comprehensiveness. Working with the American Academy of Pediatrics, newly developed guidelines will be logically analyzed and verified prior to publication. (3) To evaluate the effectiveness of a guideline-based, decision support device to improve compliance with a national guideline for outpatient management of asthma in children. A randomized, controlled trial will be conducted to measure the effect of the AsthMonitor system on guideline adherence, encounter documentation, patient outcomes, and costs of care. (4) To develop a suite of interactive computer applications that support decision making and clinical workflow for the management of a broad range of common pediatric problems. Knowledge gained from the clinical trial will be combined with workflow analysis, sound application design principles, and advanced digital technologies to create useful and usable tools for guideline implementation. Individual providers will benefit from the availability of decision support applications based on guidelines knowledge. From a public health perspective, effective implementation of evidence-based guidelines for the outpatient management of asthma and other common pediatric disorders should contribute to a reduction in inappropriate practice and to improved quality of care.