Exposure Response Relationship In Hand Arm Vibration

暴露在振动工具下会产生几个特征 影响上肢组织的疾病，统称为 被称为手-手臂振动综合症(HAVS)。美国国立卫生研究院 职业安全和健康已认识到接触和 手臂振动响应关系的三种识别方法 肌肉骨骼疾病联合会(MSDC)的焦点。这项提案代表了 来自加拿大、芬兰、瑞典和美国的调查人员的联合计划 美国将研究欧洲和北美的四个暴露在振动中的队列。 他们是芬兰的Suomossalmi森林工人队列，沃尔沃卡车驾驶室 Umea的组装工人，Umea的电船造船厂工人 康涅狄格州和康涅狄格州的牙科卫生员接触高频率 震动。牙齿卫生员似乎经历了快速发病的伤害 手指上的机械感受器。这三个行业队列一直是 研究；他们的重新研究反映了利用现有暴露数据的意图， 并在健康影响已被量化的情况下确保队列参与 以及有可用的先前研究的地方。后一点很重要，因为 拟议的研究期可能太短，无法理解受试者内部的变化。 工作地点选择反映了暴露的变化和影响(沃尔沃) 和高频振动(牙科保健员)。GB/T14949.4-1993医学试验激光 多普勒法、冷刺激容积法、多频测振法和 分离的指神经传导--是复杂的和反射的 生理上的理解。 暴露评估是这项研究中最复杂的组成部分。它包括 队列代表和个体的振动和生物力学评估 使用个性化的数据记录器和传感器监控日常工作 手套。这种以前没有应用过的细节级别反映了 对生物力学校正后的每日实时暴露进行评估的必要性 变量。

Exposure to vibrating tools produces several characteristic disorders effecting tissues of the upper extremity, which collectively are termed the Hand-Arm Vibration Syndrome (HAVS). The National Institute of Occupational Safety and Health has recognized the importance of exposure and response relationships in hand-arm vibration by identification as one of three foci of the Musculoskeletal Disease Consortium (MSDC). This proposal represents the combined plan of investigators from Canada, Finland, Sweden and the United States to study four vibration-exposed cohorts in Europe and North America. They are the Suomossalmi forest worker cohort in Finland, the Volvo truck cab assembly workforce in Umea, the Electric Boat shipyard workforce in Connecticut, and Connecticut dental hygienists exposed to high frequency vibration. Dental hygienists appear to experience rapid onset injuries to mechanoreceptors in the fingers. The three industrial cohorts have been studied; their restudy reflects the intent to utilize existing exposure data, and to assure cohort participation where health effects have been quantified and where there are usable prior studies. The latter point is important because the proposed study period may be too brief to appreciate intra-subject change. Worksite selection reflects exposure variation and inclusion of impact (Volvo) and high frequency vibration (dental hygienists). Medical tests -- laser Doppler, cold challenge plethysmograpy, multi-frequency vibrometry, and fractionated digital nerve conduction -- are sophisticated and reflect physiologic understanding. Exposure assessment is the most complex component of this study. It includes vibratory and biomechanical assessment of cohort representatives and individual monitoring of daily work routines using individualized data loggers and sensor gloves. This level of detail, which has not been previously applied, reflects the necessity of assessing daily real time exposure corrected for biomechanical variables.