COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY

本申请的目的是记录 佛罗里达大学作为一个有效和富有成效的参与 在拟定的多中心临床试验中， “青光眼初始治疗合作研究”（CIGTS）。 这项研究的 目的是评估开角型青光眼的初始治疗是否 更有效的是通过一个阶梯，医疗方案或通过一个 手术入路。 佛罗里达大学的临床中心将 通过识别和招募合格患者参与CIGTS， 给予CIGTS分配的治疗方案 协调中心，并在研究操作手册中定义， 随访和保留研究患者，记录和转移研究 数据到协调中心，并有助于报告，将 CIGTS的结果。 此应用程序描述了佛罗里达大学 临床中心每年招募约13-26名患者，基于 在为期3个月的患者资格试点研究中， 期 详细介绍了我们的计划，以确定，招聘，遵循， 并留住这些患者，我们的意图是获得始终如一的高质量 关于治疗的视觉结果的数据，以及人员和 在我们的中心内提供的设施，以执行规定的 CIGTS的操作手册。

The intent of this application is to document the ability of the University of Florida to participate as an effective and productive clinical center in the proposed multicenter clinical trial, entitled "Collaborative Initial Glaucoma Treatment Study" (CIGTS). This study's purpose is to evaluate whether initial treatment of open angle glaucoma is more effective by means of a stepped, medical regimen or by means of a surgical approach. The University of Florida's Clinical Center will participate in the CIGTS by identifying and recruiting eligible patients, administering the treatment regimen as assigned by the CIGTS's Coordinating Center and defined within the study's Manual of Operations, following and retaining study patients, recording and transferring study data to the Coordinating Center, and contributing to reports that will present the CIGTS results. This application describes the ability of the University of Florida's Clinical Center to enroll approximately 13-26 patients per year, based upon pilot studies of patient eligibility conducted during a 3 month period. Details are provided of our plans to identify, recruit, follow, and retain these patients, our intent to obtain consistently high quality data on the visual outcomes of treatment, and the personnel and facilities available within our center to carry out the provisions of the CIGTS's Manual of operations.