A NEW FUNCTIONAL EVALUATION TOOL FOR CANCER CARE

这项研究奖有两个目标，题为“癌症护理的新功能评估工具。“首先，研究的目的是开发一种新的，病人管理的，多项选择的问卷，这将是有用的性能状态的评估。 其次，该奖项的职业发展部分将支持候选人在构建和解释定性所需的技能方面的教育，从而增强他的定量技能和进行独立，成果相关研究的能力。 癌症患者的体能状态目前使用一到两个供应商评分量表进行评估：Karnofsky体能量表和东部肿瘤协作组体能量表。 虽然这些规模已被广泛使用多年，规模发展的最新进展，最近的研究评估这两个规模表明，这两个规模都没有表现出的性能水平，可以通过一个良好的构造工具。 由于这些量表目前用于决定临床试验的治疗和资格，因此量表的结构和性能问题有可能严重影响癌症患者和癌症治疗研究。我们为申请人提出了一个在资助期内进行课堂作业、自学和量表开发的综合计划，我们希望这将产生一个改进的身体功能测量。 该量表将通过四个步骤构建。 1)通过访谈确定构成结构“功能”的领域。 2)编写和测试反映这些领域的问题。 3)评估领域和问题的信度、结构效度和预测效度。 4)通过对仪器组装结果的分析进行信度和效度检验，然后对结果进行传播。

There are two objectives for this research award, entitled "A new functional evaluation tool for cancer care." First, the research aim is to develop a new, patient administered, multiple choice questionnaire that will be useful in the assessment of performance status. Second, the career development portion of the award will support the education of the candidate in the skills necessary to construct and interpret qualitative, thus augmenting his quantitative skills and his ability to perform independent, outcomes related research. The performance status of patients with cancer is currently assessed using one to two provider scored scales: the Karnofsky Performance Scale and the Eastern Cooperative Oncology Group performance scale. Although these scales have been seen wide use for many years, recent advances in scale development, and recent research evaluating these two scales have demonstrated that neither of these scales demonstrates the level of performance that could be achieved through a well constructed instrument. As these scale are currently used to make decisions about therapies and eligibility for clinical trials, structural and performance problems with the scales have the potential to substantially affect both patients with cancer, and research on cancer treatment. We propose for the applicant a combined program fo classwork, self study, and scale development over the grant period that we hope will yield an improved measure of physical function. The scale will be constructed through a four step process. 1) Identification of domains through interviews that make up the construct 'function'. 2) Writing and testing of questions that reflect these domains. 3) Assessment of reliability, construct validity, and predictive validity of the domains and the questions. 4) Instrument assembly through analysis of results of reliability and validity testing, followed by dissemination of results.