A NEW FUNCTIONAL EVALUATION TOOL FOR CANCER CARE

一种新的癌症治疗功能评估工具

• 批准号: 6522632
• 负责人: PETER B. BACH
• 金额: $ 9.88万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2005-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6522632
• 关键词: behavioral /social science research tag; bone marrow neoplasms; breast neoplasms; clinical research; colon neoplasms; experimental designs; functional ability; health care service evaluation; health services research tag; human subject; human therapy evaluation; interview; lung neoplasms; neoplasm /cancer therapy; patient care; prognosis; prostate neoplasms; questionnaires

There are two objectives for this research award, entitled "A new functional evaluation tool for cancer care." First, the research aim is to develop a new, patient administered, multiple choice questionnaire that will be useful in the assessment of performance status. Second, the career development portion of the award will support the education of the candidate in the skills necessary to construct and interpret qualitative, thus augmenting his quantitative skills and his ability to perform independent, outcomes related research. The performance status of patients with cancer is currently assessed using one to two provider scored scales: the Karnofsky Performance Scale and the Eastern Cooperative Oncology Group performance scale. Although these scales have been seen wide use for many years, recent advances in scale development, and recent research evaluating these two scales have demonstrated that neither of these scales demonstrates the level of performance that could be achieved through a well constructed instrument. As these scale are currently used to make decisions about therapies and eligibility for clinical trials, structural and performance problems with the scales have the potential to substantially affect both patients with cancer, and research on cancer treatment. We propose for the applicant a combined program fo classwork, self study, and scale development over the grant period that we hope will yield an improved measure of physical function. The scale will be constructed through a four step process. 1) Identification of domains through interviews that make up the construct 'function'. 2) Writing and testing of questions that reflect these domains. 3) Assessment of reliability, construct validity, and predictive validity of the domains and the questions. 4) Instrument assembly through analysis of results of reliability and validity testing, followed by dissemination of results.

该研究奖有两个目标，题为“癌症护理的新功能评估工具”。 首先，研究目的是开发一种新的、由患者管理的多项选择问卷，该问卷将有助于评估表现状态。 其次，该奖项的职业发展部分将支持对候选人进行构建和解释定性所需技能的教育，从而增强他的定量技能和进行独立的、与结果相关的研究的能力。 目前，癌症患者的体能状态使用一到两个提供者评分量表进行评估：卡诺夫斯基体能量表和东部肿瘤合作组体能量表。 尽管这些量表已广泛使用多年，但量表开发的最新进展以及最近评估这两种量表的研究表明，这两种量表都没有表现出通过精心构建的仪器可以实现的性能水平。 由于这些量表目前用于做出有关治疗和临床试验资格的决定，因此量表的结构和性能问题有可能对癌症患者和癌症治疗研究产生重大影响。我们为申请人提出了在资助期内进行课堂作业、自学和量表开发的综合计划，我们希望这将改善身体机能的测量。 该量表将通过四个步骤构建。 1) 通过访谈识别构成“功能”结构的领域。 2) 编写和测试反映这些领域的问题。 3) 评估领域和问题的可靠性、结构有效性和预测有效性。 4) 通过分析信度和效度测试结果来组装仪器，然后发布结果。