PROSTATE NEOPLASM--DEVELOPMENTAL PROJECTS

我们将继续我们的发展研究计划，其中包括 支持调查员发起的试点项目申请的指示 以及在特定领域进行有针对性的研究， 推进SPORE的转化研究目标。 预算总额 发展研究计划将获得20万美元，其中 大约75%将用于试点项目资金，25%用于 有针对性的研究举措。 试点项目选择的优先次序 包括那些真正有创造力的，高度创新的， 尽可能高的科学质量。 这些项目还应补充 的长期研究目标，并为成功做出贡献 我们的翻译研究目标。 有针对性的研究重点 包括高度选择实验或临床计划， 根据科学顾问的判断，我们的SPORE计划中存在特定需求 以马克思 发展研究计划迄今已证明在 增长和扩大我们的孢子研究计划，并已加速 实现我们具体的翻译目标。 通过试点 项目资金，高度有才华的高级调查员一直在 被招募来专注于前列腺癌的转化研究。 在 此外，该计划在招募有前途的人才方面发挥了重要作用。 初级教师的泌尿科斯科特部门和其他贝勒 部门 在我们最初的SPORE资助期间， 已经被许多研究人员成功地转化为 同行评审的研究补助金，并在某些情况下，以发挥主导作用 孢子内。 发展研究基金使用的检讨机制， 在获得SPORE资助后，它取得了巨大的成功。 的 科学咨询委员会，在Bert W.奥马利 M.D.负责评估、优先排序和奖励 发展研究资金。 我们会维持 该委员会也将继续接受奥马利博士的指导。 但由于日益增加的责任和复杂性， 面对科学咨询委员会的决定，我们增加了两个 额外的成员。 我们对我们的功能非常乐观。 发展研究计划，并预计它将继续发挥 在我们的SPORE的成功中发挥着重要作用。

We will continue our Developmental Research Program which includes directives to support both investigator initiated pilot project application as well as targeted research in specific areas that are highly likely to advance the translational research goals of the SPORE. The total budget for the Developmental Research Program will be $200,000 of which approximately 75% will be allocated for pilot project funding and 25% for target research initiatives. Priorities for pilot project selection include those that are truly creative, highly innovative, and are of the highest possible scientific quality. These projects should also complement the long-term research goals of the SPORE and contribute toward the success of our translational research objectives. The targeted research priorities include highly select experimental or clinical initiatives that address a specific need in our SPORE program as judged by the Scientific Advisory Committee. The Developmental Research Program has thus far proved critical in the growth and expansion of our SPORE research program and has accelerated progress toward our specific translational objectives. Through pilot project funding, highly talented senior-level investigators have been recruited to focus on translational research in prostate cancer. In addition, this program has played an important role in recruiting promising junior-level faculty to the Scott Department of Urology and to other Baylor departments. During our initial SPORE-funding period, pilot project awards have been successfully converted by many investigators into substantial peer reviewed research grant awards, and in some cases, to a leading role within the SPORE. The review mechanism for use of Development Research Funds, which we initiated upon receiving SPORE funding, has been highly successful. The Scientific Advisory Committee, under the direction of Bert W. O'Malley, M.D. has assumed responsibility for evaluating, prioritizing, and awarding developmental research funding. We will maintain the basic structure of the committee, which will also remain under the direction of Dr. O'Malley. But because of the increasing responsibilities and complexity of the decisions facing of Scientific Advisory Committee, we have added two additional members. We are highly optimistic regarding the function of our Developmental Research Program and anticipate that it will continue to play a fundamental role in the success of our SPORE.