ELASTIC SCATTERED RAMAN SIGNAL IN IRRADIATED BLOOD SAMPLES

辐照血样中的弹性散射拉曼信号

• 批准号: 6121235
• 负责人: TAE-WOONG KOO
• 金额: $ 0.41万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-01 至 2000-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6121235
• 关键词: bioengineering /biomedical engineering; biological products; biomedical equipment development; biomedical resource; diabetes mellitus; human tissue; infrared radiation; model design /development; technology /technique

With our recent encouraging results indicating that NIR Raman can measure analyte concentrations in whole blood, it becomes important for us to study the manner in which NIR light explores blood samples. Two particularly important quantities are: a) the characteristic diameter of the Raman emission emerging from a blood sample irradiated by a narrow laser beam; and b) the characteristic depth of the volume probed in such a measurement. We have derived new expressions that allow us to calculate both of these quantities on the computer as a function of the optical properties of the sample and the diameter of the excitation beam. In our upcoming studies, we will generate experimental data on Raman spot size and compare it with the predictions of our model expressions.

我们最近令人鼓舞的结果表明近红外拉曼可以 测量全血中的分析物浓度，变得很重要 让我们研究近红外光探索血液样本的方式。 两个特别重要的量是： a) 特征 受辐射的血液样本发出的拉曼发射的直径 通过窄激光束； b) 体积的特征深度 在这样的测量中进行了探讨。 我们推导出了新的表达方式 允许我们在计算机上计算这两个量 样品的光学特性和直径的函数 激发光束。 在我们即将进行的研究中，我们将生成 拉曼光斑尺寸的实验数据并与 我们的模型表达式的预测。