CEREBELLAR NUCLEI IN EYE MOVEMENT CONTROL & ADAPTATION

这项研究的目标是了解小脑是如何帮助眼睛运动的。我们知道小脑在我们做的每一个动作中都很重要，但我们不知道它到底做什么或如何做。我们可以通过研究小脑的眼动比肢体或其他运动更快地取得进展，因为我们比其他任何运动都更了解大脑是如何产生眼动的。我们的研究结果还将帮助我们理解大脑如何产生眼球运动。眼球运动是我们生活中重要的一部分。每天，我们都会做数以万计的眼球运动，以观察感兴趣的东西，并清晰地看到它们。眼球运动的异常严重降低了我们阅读、观看和视觉引导其他运动的能力。在其他项目中，我们正在调查小脑在使眼球运动变得不准确后使其准确的能力所起的作用。小脑与无意识学习有关，无意识学习使我们的动作保持准确，但我们不知道它扮演着什么角色。1997年，我们发表了一篇关于正常猴子如何适应快速眼球运动的详细描述。这一描述将帮助我们研究大脑如何修改动作以保持它们的准确性。我们还发表了关于尾侧顶核在我们用来观察缓慢移动的目标的缓慢平滑追逐眼球运动中的作用的描述。最后，我们提交了一篇关于多次重复快速眼动如何影响这些动作的表现的论文。这些信息将帮助我们正确解释我们从猴子那里收集的眼动适应数据。

The goal of this research is to understand how the cerebellum aids eye movements. We know that the cerebellum is important in every movement we make, but we do not know exactly what it does or how it does it. We can make progress faster by investigating the cerebellum with eye movements than with limb or other movements because we know much more about how the brain produces eye movements than any other movements. Our results will also help us understand how the brain produces eye movements. Eye movements are an important part of our lives. Every day we make tens of thousands of eye movements to look at things of interest and see them clearly. Abnormalities in eye movements severely reduce our ability to read, see, and visually guide our other movements. Among other projects, we are investigating the role of the cerebellum in the ability to make eye movements accurate after something has made them inaccurate. The cerebellum has been implicated in the unconscious learning that keeps our movements accurate, but we do not know what role it plays. In 1997 we published a detailed description of how normal monkeys adapt their rapid eye movements. This description will help us investigate how the brain modifies movements to keep them accurate. We also published a description of the role of the caudal fastigial nucleus in the slow smooth-pursuit eye movements that we use to look at slowly moving targets. Finally, we submitted a paper on how making many repeated rapid eye movements affects the performance of these movements. This information will help us correctly interpret data on eye movement adaptation that we collect from monkeys.