DOES TWINNING INFLUENCE RELIABILITY OF THYROID NEWBORN SCREENING TEST

双胞胎是否会影响新生儿甲状腺筛查测试的可靠性

• 批准号: 6264288
• 负责人: CAROL L GREENE
• 金额: $ 1.99万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6264288
• 关键词: blood chemistry; blood transfusion; clinical chemistry; clinical research; diagnosis design /evaluation; diagnosis quality /standard; human subject; newborn human (0-6 weeks); perinatal; thyroid function; thyroid hormones; twin /multiplet

This study will test the blood thyroid values of each of the siblings of twin pregnancies at delivery, and on the first and second screening tests. It will describe any similarities and differences between the siblings and any trend in similarity or difference from birth to first and second screen, and will compare to singleton controls. If a pattern is shown to exist, the possibility that twin transfusion affects thyroid levels in utero and in the postnatal period will be examined.

这项研究将测试双胎妊娠的每个兄弟姐妹在分娩时以及第一次和第二次筛查测试时的血液甲状腺值。它将描述兄弟姐妹之间的任何相似之处和差异，以及从出生到第一和第二屏幕的相似或差异的任何趋势，并将与单例控件进行比较。 如果存在某种模式，将检查双胞胎输血影响子宫内和产后甲状腺水平的可能性。