DETERMINATION OF PROTEIN SYNTHESIS AND CATABOLISM IN NEONATES

新生儿蛋白质合成和分解代谢的测定

• 批准号: 6114955
• 负责人: PATTI THUREEN
• 金额: $ 1.99万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6114955
• 关键词: biotransformation; clinical research; dietary proteins; human subject; newborn human (0-6 weeks); nutrition; nutrition related tag; premature infant human; protein biosynthesis

The clinical circumstances of the preterm and sick infant are quite complex from a metabolic and nutritional viewpoint. The calculation of protein catabolism and synthesis in infants with a wide variety of disease states could be used as a guideline to help recognize the infants who are at a particular nutritional risk and identify those who are becoming increasingly catabolic. Information gained from this study will provide a more accurate estimate of protein requirements by neonates and potentially maximize their nutritional status.

从代谢和营养的角度来看，早产儿和患病婴儿的临床情况相当复杂。 计算具有各种疾病状态的婴儿的蛋白质代谢和合成可以用作指导方针，以帮助识别处于特定营养风险的婴儿，并确定那些正在变得越来越分解代谢的婴儿。 从本研究中获得的信息将提供新生儿蛋白质需求的更准确估计，并可能最大限度地提高他们的营养状况。